Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8851
MIM: 603460
HGNC: 1775
Ensembl: ENSG00000176749
Variants:
dbSNP: 8851
ClinVar: 8851
TCGA: ENSG00000176749
COSMIC: CDK5R1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000176749 | ENST00000313401 | Q15078 |
| ENSG00000176749 | ENST00000584716 | J3QRB5 |
| ENSG00000176749 | ENST00000584792 | J3QRB5 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37899376 | 2023 | Tumor-suppressive microRNA-152 inhibits the proliferation of Ewing's sarcoma cells by targeting CDK5R1. | 0 |
| 37899376 | 2023 | Tumor-suppressive microRNA-152 inhibits the proliferation of Ewing's sarcoma cells by targeting CDK5R1. | 0 |
| 33346796 | 2021 | Elevated CDK5R1 predicts worse prognosis in hepatocellular carcinoma based on TCGA data. | 6 |
| 33346796 | 2021 | Elevated CDK5R1 predicts worse prognosis in hepatocellular carcinoma based on TCGA data. | 6 |
| 30718749 | 2019 | The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication. | 5 |
| 30718749 | 2019 | The Cyclin-Dependent Kinase 5 Inhibitor Peptide Inhibits Herpes Simplex Virus Type 1 Replication. | 5 |
| 29997370 | 2018 | Multiple Layers of CDK5R1 Regulation in Alzheimer's Disease Implicate Long Non-Coding RNAs. | 44 |
| 29997370 | 2018 | Multiple Layers of CDK5R1 Regulation in Alzheimer's Disease Implicate Long Non-Coding RNAs. | 44 |
| 27343180 | 2017 | The miR-15/107 Family of microRNA Genes Regulates CDK5R1/p35 with Implications for Alzheimer's Disease Pathogenesis. | 48 |
| 27343180 | 2017 | The miR-15/107 Family of microRNA Genes Regulates CDK5R1/p35 with Implications for Alzheimer's Disease Pathogenesis. | 48 |
| 26657932 | 2016 | Functional characterization of CDK5 and CDK5R1 mutations identified in patients with non-syndromic intellectual disability. | 9 |
| 27387995 | 2016 | Computational study of the inhibitory mechanism of the kinase CDK5 hyperactivity by peptide p5 and derivation of a pharmacophore. | 6 |
| 26657932 | 2016 | Functional characterization of CDK5 and CDK5R1 mutations identified in patients with non-syndromic intellectual disability. | 9 |
| 27387995 | 2016 | Computational study of the inhibitory mechanism of the kinase CDK5 hyperactivity by peptide p5 and derivation of a pharmacophore. | 6 |
| 25391294 | 2015 | Sumoylation of p35 modulates p35/cyclin-dependent kinase (Cdk) 5 complex activity. | 7 |
Citation
Dessen P
CDK5R1 (cyclin dependent kinase 5 regulatory subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40034/cdk5r1
