CDKL3 (cyclin dependent kinase like 3)

2003-02-01  

Identity

HGNC
LOCATION
5q31.1
LOCUSID
ALIAS
NKIAMRE
FUSION GENES

Other Information

Locus ID:

NCBI: 51265
MIM: 608459
HGNC: 15483
Ensembl: ENSG00000006837

Variants:

dbSNP: 51265
ClinVar: 51265
TCGA: ENSG00000006837
COSMIC: CDKL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000006837ENST00000265334Q8IVW4
ENSG00000006837ENST00000518990H0YAP8
ENSG00000006837ENST00000519312E5RGK4
ENSG00000006837ENST00000520592H0YB17
ENSG00000006837ENST00000520693E5RI54
ENSG00000006837ENST00000521118E7ET86
ENSG00000006837ENST00000521755E5RFT9
ENSG00000006837ENST00000523054B4DX41
ENSG00000006837ENST00000523832Q8IVW4

Expression (GTEx)

0
5
10
15
20
25

References

Pubmed IDYearTitleCitations
366300732023CDKL3 Promotes Non-small Cell Lung Cancer by Suppressing Autophagy Via Activation of PI3K/Akt/mTOR Pathway.1
366300732023CDKL3 Promotes Non-small Cell Lung Cancer by Suppressing Autophagy Via Activation of PI3K/Akt/mTOR Pathway.1
332327362021CircTP53 promotes colorectal cancer by acting as a miR-876-3p sponge to increase cyclin-dependent kinase-like 3 expression.5
340973362021Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway.5
343298372021Bone marrow mesenchymal stem cells-secreted exosomal microRNA-205-5p exerts inhibitory effect on the progression of liver cancer through regulating CDKL3.8
344270982021Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway.1
332327362021CircTP53 promotes colorectal cancer by acting as a miR-876-3p sponge to increase cyclin-dependent kinase-like 3 expression.5
340973362021Identification of CDKL3 as a critical regulator in development of glioma through regulating RRM2 and the JNK signaling pathway.5
343298372021Bone marrow mesenchymal stem cells-secreted exosomal microRNA-205-5p exerts inhibitory effect on the progression of liver cancer through regulating CDKL3.8
344270982021Cyclin-dependent kinase like 3 promotes triple-negative breast cancer progression via inhibiting the p53 signaling pathway.1
322347502020CDKL3 promotes osteosarcoma progression by activating Akt/PKB.3
322347502020CDKL3 promotes osteosarcoma progression by activating Akt/PKB.3
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
184121092008Inactivation of the CDKL3 gene at 5q31.1 by a balanced t(X;5) translocation associated with nonspecific mild mental retardation.11

Citation

Dessen P

CDKL3 (cyclin dependent kinase like 3)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40037/cdkl3