Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CEBPZ (CCAAT enhancer binding protein zeta)

Identity

Alias_namesCCAAT/enhancer binding protein (C/EBP), zeta
CCAAT/enhancer binding proteincebp* family zeta
CCAAT/enhancer binding protein zeta
Alias_symbol (synonym)CBF2
CTF2
Other aliasCBF
HSP-CBF
NOC1
HGNC (Hugo) CEBPZ
LocusID (NCBI) 10153
Atlas_Id 52371
Location 2p22.2  [Link to chromosome band 2p22]
Location_base_pair Starts at 37201613 and ends at 37231596 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CEBPZ (2p22.2) / ECD (10q22.1)CEBPZ (2p22.2) / FUS (16p11.2)CEBPZ (2p22.2) / KRT19 (17q21.2)
CEBPZ (2p22.2) / MYH11 (16p13.11)EIF2AK2 (2p22.2) / CEBPZ (2p22.2)FUS (16p11.2) / CEBPZ (2p22.2)
EIF2AK2 2p22.2 / CEBPZ 2p22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  EIF2AK2/CEBPZ (2p22)

External links

Nomenclature
HGNC (Hugo)CEBPZ   24218
Cards
Entrez_Gene (NCBI)CEBPZ  10153  CCAAT enhancer binding protein zeta
AliasesCBF; CBF2; HSP-CBF; NOC1
GeneCards (Weizmann)CEBPZ
Ensembl hg19 (Hinxton)ENSG00000115816 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115816 [Gene_View]  ENSG00000115816 [Sequence]  chr2:37201613-37231596 [Contig_View]  CEBPZ [Vega]
ICGC DataPortalENSG00000115816
TCGA cBioPortalCEBPZ
AceView (NCBI)CEBPZ
Genatlas (Paris)CEBPZ
WikiGenes10153
SOURCE (Princeton)CEBPZ
Genetics Home Reference (NIH)CEBPZ
Genomic and cartography
GoldenPath hg38 (UCSC)CEBPZ  -     chr2:37201613-37231596 -  2p22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CEBPZ  -     2p22.2   [Description]    (hg19-Feb_2009)
GoldenPathCEBPZ - 2p22.2 [CytoView hg19]  CEBPZ - 2p22.2 [CytoView hg38]
Genome Data Viewer NCBICEBPZ [Mapview hg19]  
OMIM612828   
Gene and transcription
Genbank (Entrez)AK312322 BC034475 M37197
RefSeq transcript (Entrez)NM_005760
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CEBPZ
Alternative Splicing GalleryENSG00000115816
Gene ExpressionCEBPZ [ NCBI-GEO ]   CEBPZ [ EBI - ARRAY_EXPRESS ]   CEBPZ [ SEEK ]   CEBPZ [ MEM ]
Gene Expression Viewer (FireBrowse)CEBPZ [ Firebrowse - Broad ]
GenevisibleExpression of CEBPZ in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10153
GTEX Portal (Tissue expression)CEBPZ
Human Protein AtlasENSG00000115816-CEBPZ [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ03701   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ03701  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ03701
Splice isoforms : SwissVarQ03701
PhosPhoSitePlusQ03701
Domains : Interpro (EBI)ARM-type_fold    CCAAT-binding_factor    CEBPZ/Mak21-like   
Domain families : Pfam (Sanger)CBF (PF03914)   
Domain families : Pfam (NCBI)pfam03914   
Conserved Domain (NCBI)CEBPZ
DMDM Disease mutations10153
SuperfamilyQ03701
Human Protein Atlas [tissue]ENSG00000115816-CEBPZ [tissue]
Peptide AtlasQ03701
HPRD09875
IPIIPI00306723   IPI00893383   
Protein Interaction databases
DIP (DOE-UCLA)Q03701
IntAct (EBI)Q03701
FunCoupENSG00000115816
BioGRIDCEBPZ
STRING (EMBL)CEBPZ
ZODIACCEBPZ
Ontologies - Pathways
QuickGOQ03701
Ontology : AmiGORNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  RNA binding  nucleus  transcription by RNA polymerase II  ribosome biogenesis  positive regulation of transcription by RNA polymerase II  
Ontology : EGO-EBIRNA polymerase II proximal promoter sequence-specific DNA binding  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA-binding transcription activator activity, RNA polymerase II-specific  DNA binding  RNA binding  nucleus  transcription by RNA polymerase II  ribosome biogenesis  positive regulation of transcription by RNA polymerase II  
NDEx NetworkCEBPZ
Atlas of Cancer Signalling NetworkCEBPZ
Wikipedia pathwaysCEBPZ
Orthology - Evolution
OrthoDB10153
GeneTree (enSembl)ENSG00000115816
Phylogenetic Trees/Animal Genes : TreeFamCEBPZ
HOGENOMQ03701
Homologs : HomoloGeneCEBPZ
Homology/Alignments : Family Browser (UCSC)CEBPZ
Gene fusions - Rearrangements
Fusion : MitelmanEIF2AK2/CEBPZ [2p22.2/2p22.2]  
Fusion PortalEIF2AK2 2p22.2 CEBPZ 2p22.2 BLCA BRCA
Fusion : QuiverCEBPZ
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCEBPZ [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CEBPZ
dbVarCEBPZ
ClinVarCEBPZ
1000_GenomesCEBPZ 
Exome Variant ServerCEBPZ
GNOMAD BrowserENSG00000115816
Varsome BrowserCEBPZ
Genetic variants : HAPMAP10153
Genomic Variants (DGV)CEBPZ [DGVbeta]
DECIPHERCEBPZ [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCEBPZ 
Mutations
ICGC Data PortalCEBPZ 
TCGA Data PortalCEBPZ 
Broad Tumor PortalCEBPZ
OASIS PortalCEBPZ [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCEBPZ  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCEBPZ
Mutations and Diseases : HGMDCEBPZ
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect CEBPZ
DgiDB (Drug Gene Interaction Database)CEBPZ
DoCM (Curated mutations)CEBPZ (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CEBPZ (select a term)
intoGenCEBPZ
Cancer3DCEBPZ (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612828   
Orphanet
DisGeNETCEBPZ
MedgenCEBPZ
Genetic Testing Registry CEBPZ
NextProtQ03701 [Medical]
TSGene10153
GENETestsCEBPZ
Open Targets GeneticsENSG00000115816  [validation]
snp3D : Map Gene to Disease10153
BioCentury BCIQCEBPZ
ClinGenCEBPZ
Clinical trials, drugs, therapy
Protein Interactions : CTD10153
Pharm GKB GenePA134977051
Clinical trialCEBPZ
Miscellaneous
canSAR (ICR)CEBPZ (select the gene name)
HarmonizomeCEBPZ
DataMed IndexCEBPZ
Probes
Litterature
PubMed62 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCEBPZ
EVEXCEBPZ
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 19:42:59 CEST 2020
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