Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23436
MIM: 618694
HGNC: 15945
Ensembl: ENSG00000219073
Variants:
dbSNP: 23436
ClinVar: 23436
TCGA: ENSG00000219073
COSMIC: CELA3B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000219073 | ENST00000337107 | P08861 |
| ENSG00000219073 | ENST00000400277 | A0A0A0MSA6 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Pancreatic secretion | KEGG | ko04972 |
| Pancreatic secretion | KEGG | hsa04972 |
| Protein digestion and absorption | KEGG | ko04974 |
| Protein digestion and absorption | KEGG | hsa04974 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36610873 | 2023 | Utility of Fecal Elastase-1 to diagnose severe exocrine insufficiency in chronic pancreatitis: Real world experience. | 2 |
| 37307306 | 2023 | Does the Complex of CELA3B Variants With Other Pancreatitis-Related Genes Affect Developing Childhood Pancreatitis? | 0 |
| 36610873 | 2023 | Utility of Fecal Elastase-1 to diagnose severe exocrine insufficiency in chronic pancreatitis: Real world experience. | 2 |
| 37307306 | 2023 | Does the Complex of CELA3B Variants With Other Pancreatitis-Related Genes Affect Developing Childhood Pancreatitis? | 0 |
| 33565216 | 2021 | The reversion variant (p.Arg90Leu) at the evolutionarily adaptive p.Arg90 site in CELA3B predisposes to chronic pancreatitis. | 2 |
| 33565216 | 2021 | The reversion variant (p.Arg90Leu) at the evolutionarily adaptive p.Arg90 site in CELA3B predisposes to chronic pancreatitis. | 2 |
| 31369399 | 2019 | Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma. | 7 |
| 31369399 | 2019 | Elastase 3B mutation links to familial pancreatitis with diabetes and pancreatic adenocarcinoma. | 7 |
| 30106003 | 2018 | Fecal pancreatic elastase-1 and erythrocyte magnesium levels in diabetes type 1 and type 2. | 1 |
| 30106003 | 2018 | Fecal pancreatic elastase-1 and erythrocyte magnesium levels in diabetes type 1 and type 2. | 1 |
| 27069032 | 2016 | Pancreatic Elastase Levels in Feces As A Marker of Exocrine Pancreatic Function in Patients With Diabetes Mellitus. | 3 |
| 27358403 | 2016 | Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2. | 18 |
| 27999401 | 2016 | Genetic Analysis of Human Chymotrypsin-Like Elastases 3A and 3B (CELA3A and CELA3B) to Assess the Role of Complex Formation between Proelastases and Procarboxypeptidases in Chronic Pancreatitis. | 7 |
| 27069032 | 2016 | Pancreatic Elastase Levels in Feces As A Marker of Exocrine Pancreatic Function in Patients With Diabetes Mellitus. | 3 |
| 27358403 | 2016 | Complex Formation of Human Proelastases with Procarboxypeptidases A1 and A2. | 18 |
Citation
Dessen P
CELA3B (chymotrypsin like elastase 3B)
Atlas Genet Cytogenet Oncol Haematol. 2010-10-01
Online version: http://atlasgeneticsoncology.org/gene/51704/cela3b
