Identity
HGNC
LOCATION
13q12.12
LOCUSID
ALIAS
BM032,CENP-J,CPAP,LAP,LIP1,MCPH6,SASS4,SCKL4,Sas-4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55835
MIM: 609279
HGNC: 17272
Ensembl: ENSG00000151849
Variants:
dbSNP: 55835
ClinVar: 55835
TCGA: ENSG00000151849
COSMIC: CENPJ
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000151849 | ENST00000381884 | Q9HC77 |
| ENSG00000151849 | ENST00000418179 | H0Y5L8 |
| ENSG00000151849 | ENST00000545981 | F6VUX8 |
| ENSG00000151849 | ENST00000616936 | Q9HC77 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37823337 | 2023 | Separation-of-function MCPH-associated mutations in CPAP affect centriole number and length. | 0 |
| 37823337 | 2023 | Separation-of-function MCPH-associated mutations in CPAP affect centriole number and length. | 0 |
| 35281599 | 2022 | Identification of Pathogenic Mutations in Primary Microcephaly- (MCPH-) Related Three Genes CENPJ, CASK, and MCPH1 in Consanguineous Pakistani Families. | 3 |
| 35404385 | 2022 | CPAP insufficiency leads to incomplete centrioles that duplicate but fragment. | 9 |
| 35738280 | 2022 | A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection. | 7 |
| 35281599 | 2022 | Identification of Pathogenic Mutations in Primary Microcephaly- (MCPH-) Related Three Genes CENPJ, CASK, and MCPH1 in Consanguineous Pakistani Families. | 3 |
| 35404385 | 2022 | CPAP insufficiency leads to incomplete centrioles that duplicate but fragment. | 9 |
| 35738280 | 2022 | A genome-wide CRISPR-Cas9 screen identifies CENPJ as a host regulator of altered microtubule organization during Plasmodium liver infection. | 7 |
| 34135376 | 2021 | Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR. | 0 |
| 34135376 | 2021 | Centrosomal P4.1-associated protein (CPAP) positively regulates endocytic vesicular transport and lysosome targeting of EGFR. | 0 |
| 31511651 | 2020 | CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity. | 20 |
| 31511651 | 2020 | CPAP promotes angiogenesis and metastasis by enhancing STAT3 activity. | 20 |
| 29778912 | 2018 | Alcohol inhibits the proliferation of Neuro2a cells via promoting the asymmetric cell division through down-regulation of the expression of centrosome protein-J. | 3 |
| 29778912 | 2018 | Alcohol inhibits the proliferation of Neuro2a cells via promoting the asymmetric cell division through down-regulation of the expression of centrosome protein-J. | 3 |
| 26929011 | 2016 | CPAP promotes timely cilium disassembly to maintain neural progenitor pool. | 119 |
Citation
Dessen P
CENPJ (centromere protein J)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/40058/cenpj
