CENPM (centromere protein M)

2016-10-01  

Identity

HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
C22orf18,CENP-M,PANE1

Other Information

Locus ID:

NCBI: 79019
MIM: 610152
HGNC: 18352
Ensembl: ENSG00000100162

Variants:

dbSNP: 79019
ClinVar: 79019
TCGA: ENSG00000100162
COSMIC: CENPM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100162ENST00000215980Q9NSP4
ENSG00000100162ENST00000215980A0A024R1Q3
ENSG00000100162ENST00000402338B1AHQ6
ENSG00000100162ENST00000402420B1AHQ8
ENSG00000100162ENST00000404067B1AHQ7
ENSG00000100162ENST00000407253Q9NSP4
ENSG00000100162ENST00000472374Q9NSP4

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Chromosome MaintenanceREACTOMER-HSA-73886
Nucleosome assemblyREACTOMER-HSA-774815
Deposition of new CENPA-containing nucleosomes at the centromereREACTOMER-HSA-606279

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
166224192006The human CENP-A centromeric nucleosome-associated complex.295
250061652014The pseudo GTPase CENP-M drives human kinetochore assembly.46
163910152006The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL.38
197732792009Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.6
151833052004The proliferation associated nuclear element (PANE1) is conserved between mammals and fish and preferentially expressed in activated lymphoid cells.5
317035912019Upregulation of CENPM promotes hepatocarcinogenesis through mutiple mechanisms.2

Citation

Dessen P

CENPM (centromere protein M)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56435/cenpm