CENPO (centromere protein O)

2014-11-01  

Identity

HGNC
LOCATION
2p23.3
LOCUSID
ALIAS
CENP-O,ICEN-36,MCM21R
FUSION GENES

Other Information

Locus ID:

NCBI: 79172
MIM: 611504
HGNC: 28152
Ensembl: ENSG00000138092

Variants:

dbSNP: 79172
ClinVar: 79172
TCGA: ENSG00000138092
COSMIC: CENPO

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000138092ENST00000260662Q9BU64
ENSG00000138092ENST00000380834Q9BU64
ENSG00000138092ENST00000473706Q9BU64

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Signal TransductionREACTOMER-HSA-162582
Signaling by Rho GTPasesREACTOMER-HSA-194315
RHO GTPase EffectorsREACTOMER-HSA-195258
RHO GTPases Activate ForminsREACTOMER-HSA-5663220
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
M PhaseREACTOMER-HSA-68886
Mitotic PrometaphaseREACTOMER-HSA-68877
Resolution of Sister Chromatid CohesionREACTOMER-HSA-2500257
Mitotic Metaphase and AnaphaseREACTOMER-HSA-2555396
Mitotic AnaphaseREACTOMER-HSA-68882
Separation of Sister ChromatidsREACTOMER-HSA-2467813
Chromosome MaintenanceREACTOMER-HSA-73886
Nucleosome assemblyREACTOMER-HSA-774815
Deposition of new CENPA-containing nucleosomes at the centromereREACTOMER-HSA-606279

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
230285902012Step-wise assembly, maturation and dynamic behavior of the human CENP-P/O/R/Q/U kinetochore sub-complex.14
192868532009CENP-O, a protein localized at the centromere throughout the cell cycle, is a novel target antigen in systemic sclerosis.7
314856752019CENPO expression regulates gastric cancer cell proliferation and is associated with poor patient prognosis.0

Citation

Dessen P

CENPO (centromere protein O)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61709/cenpo