CEP63 (centrosomal protein 63)

2007-02-01  

Identity

HGNC
LOCATION
3q22.2
LOCUSID
ALIAS
SCKL6
FUSION GENES

Other Information

Locus ID:

NCBI: 80254
MIM: 614724
HGNC: 25815
Ensembl: ENSG00000182923

Variants:

dbSNP: 80254
ClinVar: 80254
TCGA: ENSG00000182923
COSMIC: CEP63

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182923ENST00000332047Q96MT8
ENSG00000182923ENST00000337090Q96MT8
ENSG00000182923ENST00000354446Q96MT8
ENSG00000182923ENST00000383229Q96MT8
ENSG00000182923ENST00000504929H0YAE6
ENSG00000182923ENST00000508778H0Y900
ENSG00000182923ENST00000511574D6RAY6
ENSG00000182923ENST00000512894D6R9Q4
ENSG00000182923ENST00000513612Q96MT8
ENSG00000182923ENST00000514678H0YAL1
ENSG00000182923ENST00000606977Q96MT8
ENSG00000182923ENST00000620544Q96MT8
ENSG00000182923ENST00000650279A0A3B3IT05

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Cilium AssemblyREACTOMER-HSA-5617833
Anchoring of the basal body to the plasma membraneREACTOMER-HSA-5620912
Cell CycleREACTOMER-HSA-1640170
Cell Cycle, MitoticREACTOMER-HSA-69278
Mitotic G2-G2/M phasesREACTOMER-HSA-453274
G2/M TransitionREACTOMER-HSA-69275
Regulation of PLK1 Activity at G2/M TransitionREACTOMER-HSA-2565942
Centrosome maturationREACTOMER-HSA-380287
Recruitment of mitotic centrosome proteins and complexesREACTOMER-HSA-380270
Loss of proteins required for interphase microtubule organization from the centrosomeREACTOMER-HSA-380284
Loss of Nlp from mitotic centrosomesREACTOMER-HSA-380259
AURKA Activation by TPX2REACTOMER-HSA-8854518

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
359893682022CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1.3
359893682022CEP63 upregulates YAP1 to promote colorectal cancer progression through stabilizing RNA binding protein FXR1.3
334723042021[Study on Cep63 expression and apoptosis of thyroid papillary carcinoma cell lines TPC-1].0
341563112021Polymorphism in miRNA target sites of CEP-63 and CEP-152 ring complex influences expression of CEP genes and favors tumorigenesis in glioma.0
342963022021Cep63 knockout inhibits the malignant phenotypes of papillary thyroid cancer cell line TPC‑1.2
334723042021[Study on Cep63 expression and apoptosis of thyroid papillary carcinoma cell lines TPC-1].0
341563112021Polymorphism in miRNA target sites of CEP-63 and CEP-152 ring complex influences expression of CEP genes and favors tumorigenesis in glioma.0
342963022021Cep63 knockout inhibits the malignant phenotypes of papillary thyroid cancer cell line TPC‑1.2
321522522020Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication.15
324022862020CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression.9
321522522020Requirement of the Cep57-Cep63 Interaction for Proper Cep152 Recruitment and Centriole Duplication.15
324022862020CCDC57 Cooperates with Microtubules and Microcephaly Protein CEP63 and Regulates Centriole Duplication and Mitotic Progression.9
308583762019Molecular architecture of a cylindrical self-assembly at human centrosomes.22
308583762019Molecular architecture of a cylindrical self-assembly at human centrosomes.22
256436992015Cep63 recruits cdk1 to the centrosome-letter.1

Citation

Dessen P

CEP63 (centrosomal protein 63)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46318/cep63