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CERT1 (ceramide transporter 1)

Identity

Alias_namesCOL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
collagen type IV alpha 3 binding protein
Alias_symbol (synonym)GPBP
STARD11
CERT
Other aliasCERTL
MRD34
HGNC (Hugo) CERT1
LocusID (NCBI) 10087
Atlas_Id 58122
Location 5q13.3  [Link to chromosome band 5q13]
Location_base_pair Starts at 75368486 and ends at 75511629 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute


External links

Nomenclature
HGNC (Hugo)CERT1   2205
Cards
Entrez_Gene (NCBI)CERT1  10087  ceramide transporter 1
AliasesCERT; CERTL; COL4A3BP; GPBP; 
MRD34; STARD11
GeneCards (Weizmann)CERT1
Ensembl hg19 (Hinxton)ENSG00000113163 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113163 [Gene_View]  ENSG00000113163 [Sequence]  chr5:75368486-75511629 [Contig_View]  CERT1 [Vega]
ICGC DataPortalENSG00000113163
TCGA cBioPortalCERT1
AceView (NCBI)CERT1
Genatlas (Paris)CERT1
WikiGenes10087
SOURCE (Princeton)CERT1
Genetics Home Reference (NIH)CERT1
Genomic and cartography
GoldenPath hg38 (UCSC)CERT1  -     chr5:75368486-75511629 -  -   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CERT1  -     -   [Description]    (hg19-Feb_2009)
GoldenPathCERT1 - - [CytoView hg19]  CERT1 - - [CytoView hg38]
Genome Data Viewer NCBICERT1 [Mapview hg19]  
OMIM604677   616351   
Gene and transcription
Genbank (Entrez)AF136450 AF232930 AK000604 AK091851 AK096854
RefSeq transcript (Entrez)NM_001130105 NM_001379002 NM_001379003 NM_001379004 NM_001379029 NM_005713 NM_031361
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CERT1
Alternative Splicing GalleryENSG00000113163
Gene ExpressionCERT1 [ NCBI-GEO ]   CERT1 [ EBI - ARRAY_EXPRESS ]   CERT1 [ SEEK ]   CERT1 [ MEM ]
Gene Expression Viewer (FireBrowse)CERT1 [ Firebrowse - Broad ]
GenevisibleExpression of CERT1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10087
GTEX Portal (Tissue expression)CERT1
Human Protein AtlasENSG00000113163-CERT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y5P4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y5P4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y5P4
Splice isoforms : SwissVarQ9Y5P4
PhosPhoSitePlusQ9Y5P4
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    START (PS50848)   
Domains : Interpro (EBI)PH-like_dom_sf    PH_domain    STARD11_START    START-like_dom_sf    START_lipid-bd_dom   
Domain families : Pfam (Sanger)PH (PF00169)    START (PF01852)   
Domain families : Pfam (NCBI)pfam00169    pfam01852   
Domain families : Smart (EMBL)PH (SM00233)  START (SM00234)  
Conserved Domain (NCBI)CERT1
DMDM Disease mutations10087
PDB (RSDB)2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
PDB Europe2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
PDB (PDBSum)2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
PDB (IMB)2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
Structural Biology KnowledgeBase2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
SCOP (Structural Classification of Proteins)2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
CATH (Classification of proteins structures)2E3M    2E3N    2E3O    2E3P    2E3Q    2E3R    2E3S    2RSG    2Z9Y    2Z9Z    3H3Q    3H3R    3H3S    3H3T    4HHV    5JJD    5ZYG    5ZYH    5ZYI    5ZYJ    5ZYK    5ZYL    5ZYM    6IEZ    6IF0    6J0O    6J81   
SuperfamilyQ9Y5P4
Human Protein Atlas [tissue]ENSG00000113163-CERT1 [tissue]
Peptide AtlasQ9Y5P4
IPIIPI00024701   IPI00182914   IPI00657692   IPI00964526   IPI00964762   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y5P4
IntAct (EBI)Q9Y5P4
FunCoupENSG00000113163
BioGRIDCERT1
STRING (EMBL)CERT1
ZODIACCERT1
Ontologies - Pathways
QuickGOQ9Y5P4
Ontology : AmiGOcell morphogenesis  in utero embryonic development  heart morphogenesis  protein binding  nucleoplasm  mitochondrion  endoplasmic reticulum membrane  Golgi apparatus  Golgi apparatus  cytosol  cytosol  ceramide metabolic process  muscle contraction  immune response  endoplasmic reticulum organization  signal transduction  cell proliferation  lipid binding  membrane  kinase activity  phosphorylation  sphingolipid biosynthetic process  response to endoplasmic reticulum stress  ER to Golgi ceramide transport  ER to Golgi ceramide transport  ceramide transport  perinuclear region of cytoplasm  lipid homeostasis  phosphatidylinositol-4-phosphate binding  mitochondrion morphogenesis  ceramide binding  intermembrane lipid transfer  intermembrane sphingolipid transfer  intermembrane ceramide transfer activity  ceramide 1-phosphate binding  ceramide 1-phosphate transporter activity  ceramide 1-phosphate transport  
Ontology : EGO-EBIcell morphogenesis  in utero embryonic development  heart morphogenesis  protein binding  nucleoplasm  mitochondrion  endoplasmic reticulum membrane  Golgi apparatus  Golgi apparatus  cytosol  cytosol  ceramide metabolic process  muscle contraction  immune response  endoplasmic reticulum organization  signal transduction  cell proliferation  lipid binding  membrane  kinase activity  phosphorylation  sphingolipid biosynthetic process  response to endoplasmic reticulum stress  ER to Golgi ceramide transport  ER to Golgi ceramide transport  ceramide transport  perinuclear region of cytoplasm  lipid homeostasis  phosphatidylinositol-4-phosphate binding  mitochondrion morphogenesis  ceramide binding  intermembrane lipid transfer  intermembrane sphingolipid transfer  intermembrane ceramide transfer activity  ceramide 1-phosphate binding  ceramide 1-phosphate transporter activity  ceramide 1-phosphate transport  
NDEx NetworkCERT1
Atlas of Cancer Signalling NetworkCERT1
Wikipedia pathwaysCERT1
Orthology - Evolution
OrthoDB10087
GeneTree (enSembl)ENSG00000113163
Phylogenetic Trees/Animal Genes : TreeFamCERT1
HOGENOMQ9Y5P4
Homologs : HomoloGeneCERT1
Homology/Alignments : Family Browser (UCSC)CERT1
Gene fusions - Rearrangements
Fusion : QuiverCERT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCERT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CERT1
dbVarCERT1
ClinVarCERT1
1000_GenomesCERT1 
Exome Variant ServerCERT1
GNOMAD BrowserENSG00000113163
Varsome BrowserCERT1
Genetic variants : HAPMAP10087
Genomic Variants (DGV)CERT1 [DGVbeta]
DECIPHERCERT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCERT1 
Mutations
ICGC Data PortalCERT1 
TCGA Data PortalCERT1 
Broad Tumor PortalCERT1
OASIS PortalCERT1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCERT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutaselect CERT1
DgiDB (Drug Gene Interaction Database)CERT1
DoCM (Curated mutations)CERT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CERT1 (select a term)
intoGenCERT1
Cancer3DCERT1 (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604677    616351   
Orphanet
DisGeNETCERT1
MedgenCERT1
Genetic Testing Registry CERT1
NextProtQ9Y5P4 [Medical]
TSGene10087
GENETestsCERT1
Open Targets GeneticsENSG00000113163  [validation]
snp3D : Map Gene to Disease10087
BioCentury BCIQCERT1
ClinGenCERT1
Clinical trials, drugs, therapy
Protein Interactions : CTD10087
Clinical trialCERT1
Miscellaneous
canSAR (ICR)CERT1 (select the gene name)
HarmonizomeCERT1
DataMed IndexCERT1
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCERT1
EVEXCERT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 19:43:11 CEST 2020

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