CES3 (carboxylesterase 3)

2014-11-01  

Identity

HGNC
LOCATION
16q22.1
LOCUSID
ALIAS
ES31

Other Information

Locus ID:

NCBI: 23491
MIM: 605279
HGNC: 1865
Ensembl: ENSG00000172828

Variants:

dbSNP: 23491
ClinVar: 23491
TCGA: ENSG00000172828
COSMIC: CES3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000172828ENST00000303334Q6UWW8
ENSG00000172828ENST00000394037A0A0C4DFY7
ENSG00000172828ENST00000543856Q6UWW8
ENSG00000172828ENST00000566453H3BRE5
ENSG00000172828ENST00000570236H3BUA3

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Lipid digestion, mobilization, and transportREACTOMER-HSA-73923
Lipoprotein metabolismREACTOMER-HSA-174824
LDL-mediated lipid transportREACTOMER-HSA-171052
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
195081812009Human carboxylesterases: an update on CES1, CES2 and CES3.26
187947282008Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes.21
204224402010Mammalian carboxylesterase 3: comparative genomics and proteomics.8
205297632010Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.8
227007922012Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing.8

Citation

Dessen P

CES3 (carboxylesterase 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61744/ces3