Identity
HGNC
LOCATION
4q25
LOCUSID
ALIAS
AHUS3,ARMD13,C3BINA,C3b-INA,FI,IF,KAF
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 3426
MIM: 217030
HGNC: 5394
Ensembl: ENSG00000205403
Variants:
dbSNP: 3426
ClinVar: 3426
TCGA: ENSG00000205403
COSMIC: CFI
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38134378 | 2024 | CNS Inflammation as the First Sign of Complement Factor I Deficiency: A Severe Myelitis Treated With Intense Immunotherapy and Eculizumab. | 1 |
| 38395390 | 2024 | Elevated expression of complement factor I in lung cancer cells associates with shorter survival-Potentially via non-canonical mechanism. | 0 |
| 38423159 | 2024 | Hot Spot of Complement Factor I Rare Variant p.Ile357Met in Patients With Hemolytic Uremic Syndrome. | 0 |
| 38134378 | 2024 | CNS Inflammation as the First Sign of Complement Factor I Deficiency: A Severe Myelitis Treated With Intense Immunotherapy and Eculizumab. | 1 |
| 38395390 | 2024 | Elevated expression of complement factor I in lung cancer cells associates with shorter survival-Potentially via non-canonical mechanism. | 0 |
| 38423159 | 2024 | Hot Spot of Complement Factor I Rare Variant p.Ile357Met in Patients With Hemolytic Uremic Syndrome. | 0 |
| 37363824 | 2023 | Mutations in atypical hemolytic uremic syndrome provide evidence for the role of calcium in complement factor I. | 0 |
| 37478687 | 2023 | Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic. | 4 |
| 37363824 | 2023 | Mutations in atypical hemolytic uremic syndrome provide evidence for the role of calcium in complement factor I. | 0 |
| 37478687 | 2023 | Complement factor I: Regulatory nexus, driver of immunopathology, and therapeutic. | 4 |
| 35531992 | 2022 | Functional analysis of rare genetic variants in complement factor I in advanced age-related macular degeneration. | 5 |
| 36067162 | 2022 | An assessment of prevalence of Type 1 CFI rare variants in European AMD, and why lack of broader genetic data hinders development of new treatments and healthcare access. | 1 |
| 36643920 | 2022 | A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative CFI variants in age-related macular degeneration. | 3 |
| 35531992 | 2022 | Functional analysis of rare genetic variants in complement factor I in advanced age-related macular degeneration. | 5 |
| 36067162 | 2022 | An assessment of prevalence of Type 1 CFI rare variants in European AMD, and why lack of broader genetic data hinders development of new treatments and healthcare access. | 1 |
Citation
Dessen P
CFI (complement factor I)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47652/cfi
