Identity
HGNC
LOCATION
21q22.12
LOCUSID
ALIAS
CAF-1,CAF-IP60,CAF1,CAF1A,CAF1P60,MPHOSPH7,MPP7
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8208
MIM: 601245
HGNC: 1911
Ensembl: ENSG00000159259
Variants:
dbSNP: 8208
ClinVar: 8208
TCGA: ENSG00000159259
COSMIC: CHAF1B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000159259 | ENST00000314103 | Q13112 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37129573 | 2023 | The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability. | 5 |
| 37377894 | 2023 | Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells. | 0 |
| 37129573 | 2023 | The histone H3/H4 chaperone CHAF1B prevents the mislocalization of CENP-A for chromosomal stability. | 5 |
| 37377894 | 2023 | Targeting CHAF1B Enhances IFN Activity against Myeloproliferative Neoplasm Cells. | 0 |
| 35074917 | 2022 | CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection. | 13 |
| 35074917 | 2022 | CHAF1A/B mediate silencing of unintegrated HIV-1 DNAs early in infection. | 13 |
| 30720130 | 2019 | CHAF1B promotes proliferation and reduces apoptosis in 95‑D lung cancer cells and predicts a poor prognosis in non‑small cell lung cancer. | 11 |
| 30720130 | 2019 | CHAF1B promotes proliferation and reduces apoptosis in 95‑D lung cancer cells and predicts a poor prognosis in non‑small cell lung cancer. | 11 |
| 29767268 | 2018 | CHAF1B knockdown blocks migration in a hepatocellular carcinoma model. | 16 |
| 29767268 | 2018 | CHAF1B knockdown blocks migration in a hepatocellular carcinoma model. | 16 |
| 24039914 | 2013 | Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas. | 24 |
| 24039914 | 2013 | Prognostic significance of EDN/RB, HJURP, p60/CAF-1 and PDLI4, four new markers in high-grade gliomas. | 24 |
| 23109837 | 2012 | Tissue microarray-based evaluation of Chromatin Assembly Factor-1 (CAF-1)/p60 as tumour prognostic marker. | 15 |
| 23109837 | 2012 | Tissue microarray-based evaluation of Chromatin Assembly Factor-1 (CAF-1)/p60 as tumour prognostic marker. | 15 |
| 21109952 | 2011 | The proliferation marker Chromatin Assembly Factor-1 is of clinical value in predicting the biological behaviour of salivary gland tumours. | 16 |
Citation
Dessen P
CHAF1B (chromatin assembly factor 1 subunit B)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40068/chaf1b
