Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1103
MIM: 118490
HGNC: 1912
Ensembl: ENSG00000070748
Variants:
dbSNP: 1103
ClinVar: 1103
TCGA: ENSG00000070748
COSMIC: CHAT
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA443319 | Alzheimer Disease | Disease | ClinicalAnnotation | associated | PD | 25730470 | |
| PA447216 | Schizophrenia | Disease | ClinicalAnnotation | associated | PD | 17503482 | |
| PA449394 | donepezil | Chemical | ClinicalAnnotation | associated | PD | 25730470 | |
| PA449726 | galantamine | Chemical | ClinicalAnnotation | associated | PD | 25730470 | |
| PA450688 | olanzapine | Chemical | ClinicalAnnotation | associated | PD | 17503482 | |
| PA451262 | rivastigmine | Chemical | ClinicalAnnotation | associated | PD | 25730470 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36727317 | 2023 | Genetic associations in CHAT and COL11A1 with primary angle-closure glaucoma susceptibility: A systematic review and meta-analysis. | 0 |
| 37813167 | 2023 | Choline-acetyltransferase (ChAT) and acetylcholinesterase (AChE) in the human infant dorsal motor nucleus of the Vagus (DMNV), and alterations according to sudden infant death syndrome (SIDS) category. | 0 |
| 36727317 | 2023 | Genetic associations in CHAT and COL11A1 with primary angle-closure glaucoma susceptibility: A systematic review and meta-analysis. | 0 |
| 37813167 | 2023 | Choline-acetyltransferase (ChAT) and acetylcholinesterase (AChE) in the human infant dorsal motor nucleus of the Vagus (DMNV), and alterations according to sudden infant death syndrome (SIDS) category. | 0 |
| 34597185 | 2021 | Coronary vasodilation mediated by T cells expressing choline acetyltransferase. | 2 |
| 34743284 | 2021 | Immunohistochemical Expression of Choline Acetyltransferase and Catecholamine-Synthesizing Enzymes in Head-and-Neck and Thoracoabdominal Paragangliomas and Pheochromocytomas. | 9 |
| 34597185 | 2021 | Coronary vasodilation mediated by T cells expressing choline acetyltransferase. | 2 |
| 34743284 | 2021 | Immunohistochemical Expression of Choline Acetyltransferase and Catecholamine-Synthesizing Enzymes in Head-and-Neck and Thoracoabdominal Paragangliomas and Pheochromocytomas. | 9 |
| 28090804 | 2018 | Choline acetyltransferase may contribute to the risk of Tourette syndrome: Combination of family-based analysis and case-control study. | 2 |
| 29170094 | 2018 | The Choline Acetyltransferase (CHAT) Gene is Associated with Parahippocampal and Hippocampal Structure and Short-term Memory Span. | 0 |
| 29759072 | 2018 | CHAT gene polymorphism rs3810950 is associated with the risk of Alzheimer's disease in the Czech population. | 3 |
| 30399154 | 2018 | Genotype-ocular biometry correlation analysis of eight primary angle closure glaucoma susceptibility loci in a cohort from Northern China. | 7 |
| 28090804 | 2018 | Choline acetyltransferase may contribute to the risk of Tourette syndrome: Combination of family-based analysis and case-control study. | 2 |
| 29170094 | 2018 | The Choline Acetyltransferase (CHAT) Gene is Associated with Parahippocampal and Hippocampal Structure and Short-term Memory Span. | 0 |
| 29759072 | 2018 | CHAT gene polymorphism rs3810950 is associated with the risk of Alzheimer's disease in the Czech population. | 3 |
Citation
Dessen P
CHAT (choline O-acetyltransferase)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50359/chat
