Identity
HGNC
LOCATION
2q31.1
LOCUSID
ALIAS
ARHGAP2,CHN,DURS2,NC,RHOGAP2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1123
MIM: 118423
HGNC: 1943
Ensembl: ENSG00000128656
Variants:
dbSNP: 1123
ClinVar: 1123
TCGA: ENSG00000128656
COSMIC: CHN1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38509018 | 2024 | Special clinical features with a novel mutation site of CHN1 gene in a Chinese family with Duane retraction syndrome. | 0 |
| 38509018 | 2024 | Special clinical features with a novel mutation site of CHN1 gene in a Chinese family with Duane retraction syndrome. | 0 |
| 33667650 | 2021 | CHN1 and duane retraction syndrome: Expanding the phenotype to cranial nerves development disease. | 3 |
| 34152250 | 2021 | Bioinformatics-based analysis of the association between the A1-chimaerin (CHN1) gene and gastric cancer. | 1 |
| 34238315 | 2021 | CHN1 promotes epithelial-mesenchymal transition via the Akt/GSK-3β/Snail pathway in cervical carcinoma. | 3 |
| 33667650 | 2021 | CHN1 and duane retraction syndrome: Expanding the phenotype to cranial nerves development disease. | 3 |
| 34152250 | 2021 | Bioinformatics-based analysis of the association between the A1-chimaerin (CHN1) gene and gastric cancer. | 1 |
| 34238315 | 2021 | CHN1 promotes epithelial-mesenchymal transition via the Akt/GSK-3β/Snail pathway in cervical carcinoma. | 3 |
| 33004823 | 2020 | Identification of a novel CHN1 p.(Phe213Val) variant in a large Han Chinese family with congenital Duane retraction syndrome. | 0 |
| 33109127 | 2020 | Upregulation of miR-205 induces CHN1 expression, which is associated with the aggressive behaviour of cervical cancer cells and correlated with lymph node metastasis. | 8 |
| 33004823 | 2020 | Identification of a novel CHN1 p.(Phe213Val) variant in a large Han Chinese family with congenital Duane retraction syndrome. | 0 |
| 33109127 | 2020 | Upregulation of miR-205 induces CHN1 expression, which is associated with the aggressive behaviour of cervical cancer cells and correlated with lymph node metastasis. | 8 |
| 29872820 | 2018 | The involvement of iron in chemerin induced cell cycle arrest in human hepatic carcinoma SMMC7721 cells. | 2 |
| 29872820 | 2018 | The involvement of iron in chemerin induced cell cycle arrest in human hepatic carcinoma SMMC7721 cells. | 2 |
| 28160556 | 2017 | Prognostic significance of serum chemerin levels in patients with non-small cell lung cancer. | 25 |
Citation
Dessen P
CHN1 (chimerin 1)
Atlas Genet Cytogenet Oncol Haematol. 2004-03-01
Online version: http://atlasgeneticsoncology.org/gene/40078/chn1
