CHRD (chordin)

2007-02-01  

Identity

HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 8646
MIM: 603475
HGNC: 1949
Ensembl: ENSG00000090539

Variants:

dbSNP: 8646
ClinVar: 8646
TCGA: ENSG00000090539
COSMIC: CHRD

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000090539ENST00000204604Q9H2X0
ENSG00000090539ENST00000348986Q9H2X0
ENSG00000090539ENST00000356534Q9H2X0
ENSG00000090539ENST00000420973Q9H2X0
ENSG00000090539ENST00000448472Q9H2X0
ENSG00000090539ENST00000450923E7ESX1

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
TGF-beta signaling pathwayKEGGko04350
TGF-beta signaling pathwayKEGGhsa04350

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
265178842015The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity.9
265178842015The role of chordin fragments generated by partial tolloid cleavage in regulating BMP activity.9
239311542014Gene silencing of chordin improves BMP-2 effects on osteogenic differentiation of human adipose tissue-derived stromal cells.8
251571652014Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding.28
239311542014Gene silencing of chordin improves BMP-2 effects on osteogenic differentiation of human adipose tissue-derived stromal cells.8
251571652014Nanoscale structure of the BMP antagonist chordin supports cooperative BMP binding.28
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
190235702009Regional and cellular localisation of BMPs and their inhibitors' expression in human fractures.15
190581742009Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion.27
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.23
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
190235702009Regional and cellular localisation of BMPs and their inhibitors' expression in human fractures.15
190581742009Altered relative expression of BMPs and BMP inhibitors in cartilaginous areas of human fractures progressing towards nonunion.27
194532612009High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.23

Citation

Dessen P

CHRD (chordin)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43607/chrd