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CHST1 (carbohydrate sulfotransferase 1)

Identity

Alias_namescarbohydrate (keratan sulfate Gal-6) sulfotransferase 1
Alias_symbol (synonym)C6ST
KSGal6ST
Other aliasGST-1
KS6ST
KSST
HGNC (Hugo) CHST1
LocusID (NCBI) 8534
Atlas_Id 61819
Location 11p11.2  [Link to chromosome band 11p11]
Location_base_pair Starts at 45647689 and ends at 45665656 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCDC61 (19q13.32) / CHST1 (11p11.2)PARD6G (18q23) / CHST1 (11p11.2)PARD6G CHST1
CCDC61 CHST1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CHST1   1969
Cards
Entrez_Gene (NCBI)CHST1  8534  carbohydrate sulfotransferase 1
AliasesC6ST; GST-1; KS6ST; KSGal6ST; 
KSST
GeneCards (Weizmann)CHST1
Ensembl hg19 (Hinxton)ENSG00000175264 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175264 [Gene_View]  ENSG00000175264 [Sequence]  chr11:45647689-45665656 [Contig_View]  CHST1 [Vega]
ICGC DataPortalENSG00000175264
TCGA cBioPortalCHST1
AceView (NCBI)CHST1
Genatlas (Paris)CHST1
WikiGenes8534
SOURCE (Princeton)CHST1
Genetics Home Reference (NIH)CHST1
Genomic and cartography
GoldenPath hg38 (UCSC)CHST1  -     chr11:45647689-45665656 -  11p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHST1  -     11p11.2   [Description]    (hg19-Feb_2009)
GoldenPathCHST1 - 11p11.2 [CytoView hg19]  CHST1 - 11p11.2 [CytoView hg38]
ImmunoBaseENSG00000175264
Mapping of homologs : NCBICHST1 [Mapview hg19]  CHST1 [Mapview hg38]
OMIM603797   
Gene and transcription
Genbank (Entrez)AB003791 AF090137 AI793094 AK311168 BC022567
RefSeq transcript (Entrez)NM_003654
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHST1
Cluster EST : UnigeneHs.104576 [ NCBI ]
CGAP (NCI)Hs.104576
Alternative Splicing GalleryENSG00000175264
Gene ExpressionCHST1 [ NCBI-GEO ]   CHST1 [ EBI - ARRAY_EXPRESS ]   CHST1 [ SEEK ]   CHST1 [ MEM ]
Gene Expression Viewer (FireBrowse)CHST1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8534
GTEX Portal (Tissue expression)CHST1
Human Protein AtlasENSG00000175264-CHST1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43916   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43916  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43916
Splice isoforms : SwissVarO43916
Catalytic activity : Enzyme2.8.2.21 [ Enzyme-Expasy ]   2.8.2.212.8.2.21 [ IntEnz-EBI ]   2.8.2.21 [ BRENDA ]   2.8.2.21 [ KEGG ]   
PhosPhoSitePlusO43916
Domains : Interpro (EBI)Carbohydrate_sulfotransferase    P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)CHST1
DMDM Disease mutations8534
Blocks (Seattle)CHST1
SuperfamilyO43916
Human Protein Atlas [tissue]ENSG00000175264-CHST1 [tissue]
Peptide AtlasO43916
HPRD07051
IPIIPI00021119   
Protein Interaction databases
DIP (DOE-UCLA)O43916
IntAct (EBI)O43916
FunCoupENSG00000175264
BioGRIDCHST1
STRING (EMBL)CHST1
ZODIACCHST1
Ontologies - Pathways
QuickGOO43916
Ontology : AmiGOGolgi membrane  N-acetylglucosamine 6-O-sulfotransferase activity  trans-Golgi network  polysaccharide metabolic process  galactose metabolic process  N-acetylglucosamine metabolic process  sulfur compound metabolic process  sulfur compound metabolic process  inflammatory response  sulfotransferase activity  integral component of membrane  keratan sulfate biosynthetic process  keratan sulfate metabolic process  keratan sulfate metabolic process  keratan sulfotransferase activity  keratan sulfotransferase activity  keratan sulfotransferase activity  
Ontology : EGO-EBIGolgi membrane  N-acetylglucosamine 6-O-sulfotransferase activity  trans-Golgi network  polysaccharide metabolic process  galactose metabolic process  N-acetylglucosamine metabolic process  sulfur compound metabolic process  sulfur compound metabolic process  inflammatory response  sulfotransferase activity  integral component of membrane  keratan sulfate biosynthetic process  keratan sulfate metabolic process  keratan sulfate metabolic process  keratan sulfotransferase activity  keratan sulfotransferase activity  keratan sulfotransferase activity  
Pathways : KEGGGlycan structures - biosynthesis 1    Keratan sulfate biosynthesis   
NDEx NetworkCHST1
Atlas of Cancer Signalling NetworkCHST1
Wikipedia pathwaysCHST1
Orthology - Evolution
OrthoDB8534
GeneTree (enSembl)ENSG00000175264
Phylogenetic Trees/Animal Genes : TreeFamCHST1
HOGENOMO43916
Homologs : HomoloGeneCHST1
Homology/Alignments : Family Browser (UCSC)CHST1
Gene fusions - Rearrangements
Fusion PortalPARD6G CHST1
Fusion PortalCCDC61 CHST1
Fusion : QuiverCHST1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHST1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHST1
dbVarCHST1
ClinVarCHST1
1000_GenomesCHST1 
Exome Variant ServerCHST1
ExAC (Exome Aggregation Consortium)ENSG00000175264
GNOMAD BrowserENSG00000175264
Varsome BrowserCHST1
Genetic variants : HAPMAP8534
Genomic Variants (DGV)CHST1 [DGVbeta]
DECIPHERCHST1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHST1 
Mutations
ICGC Data PortalCHST1 
TCGA Data PortalCHST1 
Broad Tumor PortalCHST1
OASIS PortalCHST1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHST1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCHST1
Mutations and Diseases : HGMDCHST1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch CHST1
DgiDB (Drug Gene Interaction Database)CHST1
DoCM (Curated mutations)CHST1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHST1 (select a term)
intoGenCHST1
Cancer3DCHST1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603797   
Orphanet
DisGeNETCHST1
MedgenCHST1
Genetic Testing Registry CHST1
NextProtO43916 [Medical]
TSGene8534
GENETestsCHST1
Target ValidationCHST1
Huge Navigator CHST1 [HugePedia]
snp3D : Map Gene to Disease8534
BioCentury BCIQCHST1
ClinGenCHST1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8534
Chemical/Pharm GKB GenePA26501
Clinical trialCHST1
Miscellaneous
canSAR (ICR)CHST1 (select the gene name)
DataMed IndexCHST1
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHST1
EVEXCHST1
GoPubMedCHST1
iHOPCHST1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 15:23:55 CEST 2019
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