CIB1 (calcium and integrin binding 1)

2003-11-01  

Identity

HGNC
LOCATION
15q26.1
LOCUSID
ALIAS
CIB,CIBP,KIP1,PRKDCIP,SIP2-28
FUSION GENES

Other Information

Locus ID:

NCBI: 10519
MIM: 602293
HGNC: 16920
Ensembl: ENSG00000185043

Variants:

dbSNP: 10519
ClinVar: 10519
TCGA: ENSG00000185043
COSMIC: CIB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185043ENST00000328649Q99828
ENSG00000185043ENST00000328649A0A140VK09
ENSG00000185043ENST00000612800Q99828
ENSG00000185043ENST00000650306A0A3B3ISY8

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
198548312010Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1.46
155744312005Structural and biochemical characterization of CIB1 delineates a new family of EF-hand-containing proteins.38
160616952005Essential role of CIB1 in regulating PAK1 activation and cell migration.36
128812992003Calcium-and integrin-binding protein regulates focal adhesion kinase activity during platelet spreading on immobilized fibrinogen.30
127145042003Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen.29
164185302006CIB1 is an endogenous inhibitor of agonist-induced integrin alphaIIbbeta3 activation.27
149925932004Metal ion binding properties and conformational states of calcium- and integrin-binding protein.25
120232862002Molecular basis of CIB binding to the integrin alpha IIb cytoplasmic domain.23
167233532006CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel.23

Citation

Dessen P

CIB1 (calcium and integrin binding 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-11-01

Online version: http://atlasgeneticsoncology.org/gene/40083/cib1