CLDN11 (claudin 11)

2010-05-01  

Identity

HGNC
LOCATION
3q26.2
LOCUSID
ALIAS
HLD22,OSP,OTM
FUSION GENES

Other Information

Locus ID:

NCBI: 5010
MIM: 601326
HGNC: 8514
Ensembl: ENSG00000013297

Variants:

dbSNP: 5010
ClinVar: 5010
TCGA: ENSG00000013297
COSMIC: CLDN11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000013297ENST00000064724O75508

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Tight junctionKEGGko04530
Leukocyte transendothelial migrationKEGGko04670
Cell adhesion molecules (CAMs)KEGGhsa04514
Tight junctionKEGGhsa04530
Leukocyte transendothelial migrationKEGGhsa04670
Hepatitis CKEGGko05160
Hepatitis CKEGGhsa05160
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Tight junction interactionsREACTOMER-HSA-420029

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366621632023Serum claudin-5, claudin-11, occludin, vinculin, paxillin, and beta-catenin levels in preschool children with autism spectrum disorder.5
366621632023Serum claudin-5, claudin-11, occludin, vinculin, paxillin, and beta-catenin levels in preschool children with autism spectrum disorder.5
333137622021De novo stop-loss variants in CLDN11 cause hypomyelinating leukodystrophy.6
339716232021MiR-205 suppressed the malignant behaviors of breast cancer cells by targeting CLDN11 via modulation of the epithelial-to-mesenchymal transition.9
333137622021De novo stop-loss variants in CLDN11 cause hypomyelinating leukodystrophy.6
339716232021MiR-205 suppressed the malignant behaviors of breast cancer cells by targeting CLDN11 via modulation of the epithelial-to-mesenchymal transition.9
321199602020lncRNA PCAT18 inhibits proliferation, migration and invasion of gastric cancer cells through miR-135b suppression to promote CLDN11 expression.12
321199602020lncRNA PCAT18 inhibits proliferation, migration and invasion of gastric cancer cells through miR-135b suppression to promote CLDN11 expression.12
299844002019Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis.38
305141582019Impaired Localization of Claudin-11 in Endometriotic Epithelial Cells Compared to Endometrial Cells.7
306647922019Snail-induced claudin-11 prompts collective migration for tumour progression.74
315002782019Extracellular Vesicles Containing MicroRNA-92a-3p Facilitate Partial Endothelial-Mesenchymal Transition and Angiogenesis in Endothelial Cells.29
315515352019Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells.10
299844002019Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis.38
305141582019Impaired Localization of Claudin-11 in Endometriotic Epithelial Cells Compared to Endometrial Cells.7

Citation

Dessen P

CLDN11 (claudin 11)

Atlas Genet Cytogenet Oncol Haematol. 2010-05-01

Online version: http://atlasgeneticsoncology.org/gene/51464/cldn11