CLDN3 (claudin 3)

2007-02-01  

Identity

HGNC
LOCATION
7q11.23
LOCUSID
ALIAS
C7orf1,CPE-R2,CPETR2,HRVP1,RVP1

Other Information

Locus ID:

NCBI: 1365
MIM: 602910
HGNC: 2045
Ensembl: ENSG00000165215

Variants:

dbSNP: 1365
ClinVar: 1365
TCGA: ENSG00000165215
COSMIC: CLDN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165215ENST00000395145O15551
ENSG00000165215ENST00000395145Q75L79

Expression (GTEx)

0
50
100
150
200
250
300

Pathways

PathwaySourceExternal ID
Cell adhesion molecules (CAMs)KEGGko04514
Tight junctionKEGGko04530
Leukocyte transendothelial migrationKEGGko04670
Cell adhesion molecules (CAMs)KEGGhsa04514
Tight junctionKEGGhsa04530
Leukocyte transendothelial migrationKEGGhsa04670
Hepatitis CKEGGko05160
Hepatitis CKEGGhsa05160
Cell-Cell communicationREACTOMER-HSA-1500931
Cell junction organizationREACTOMER-HSA-446728
Cell-cell junction organizationREACTOMER-HSA-421270
Tight junction interactionsREACTOMER-HSA-420029

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
366063882023Claudin-3 is a novel intestinal integrity marker in patients with alopecia areata: Correlation with the disease severity.0
375785542023Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme.0
380108722023Loss of claudin-3 expression increases colitis risk by promoting Gut Dysbiosis.1
366063882023Claudin-3 is a novel intestinal integrity marker in patients with alopecia areata: Correlation with the disease severity.0
375785542023Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme.0
380108722023Loss of claudin-3 expression increases colitis risk by promoting Gut Dysbiosis.1
359456312022Tight junction formation by a claudin mutant lacking the COOH-terminal PDZ domain-binding motif.9
359456312022Tight junction formation by a claudin mutant lacking the COOH-terminal PDZ domain-binding motif.9
331470532021Comparison of claudin-3 and claudin-4 expression in bilateral and unilateral breast cancer.1
340087712021Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients.1
331470532021Comparison of claudin-3 and claudin-4 expression in bilateral and unilateral breast cancer.1
340087712021Claudin-1 and Claudin-3 as Molecular Regulators of Myelination in Leukoaraiosis Patients.1
310443872020All Benign and Malignant Apocrine Breast Lesions Over-Express Claudin 1 and 3 and Are Negative for Claudin 4.0
323074332020[Claudin-3 expression in gastric cancer].3
329455022020N‑glycosylation and receptor tyrosine kinase signaling affect claudin‑3 levels in colorectal cancer cells.10

Citation

Dessen P

CLDN3 (claudin 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46346/cldn3