Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CLEC2A (C-type lectin domain family 2 member A)

Identity

Alias_namesC-type lectin domain family 2, member A
Alias_symbol (synonym)UNQ5792
INPE5792
KACL
PILAR
Other alias
HGNC (Hugo) CLEC2A
LocusID (NCBI) 387836
Atlas_Id 51249
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 9898673 and ends at 9932381 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PAWR (12q21.2) / CLEC2A (12p13.31)PAWR 12q21.2 / CLEC2A 12p13.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CLEC2A   24191
Cards
Entrez_Gene (NCBI)CLEC2A  387836  C-type lectin domain family 2 member A
AliasesINPE5792; KACL; PILAR; UNQ5792
GeneCards (Weizmann)CLEC2A
Ensembl hg19 (Hinxton)ENSG00000188393 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188393 [Gene_View]  ENSG00000188393 [Sequence]  chr12:9898673-9932381 [Contig_View]  CLEC2A [Vega]
ICGC DataPortalENSG00000188393
TCGA cBioPortalCLEC2A
AceView (NCBI)CLEC2A
Genatlas (Paris)CLEC2A
WikiGenes387836
SOURCE (Princeton)CLEC2A
Genetics Home Reference (NIH)CLEC2A
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC2A  -     chr12:9898673-9932381 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC2A  -     12p13.31   [Description]    (hg19-Feb_2009)
GoldenPathCLEC2A - 12p13.31 [CytoView hg19]  CLEC2A - 12p13.31 [CytoView hg38]
ImmunoBaseENSG00000188393
Mapping of homologs : NCBICLEC2A [Mapview hg19]  CLEC2A [Mapview hg38]
OMIM612087   
Gene and transcription
Genbank (Entrez)AY359126 EF127467 EU095393 EU095394
RefSeq transcript (Entrez)NM_001130711 NM_207375
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC2A
Cluster EST : UnigeneHs.527665 [ NCBI ]
CGAP (NCI)Hs.527665
Alternative Splicing GalleryENSG00000188393
Gene ExpressionCLEC2A [ NCBI-GEO ]   CLEC2A [ EBI - ARRAY_EXPRESS ]   CLEC2A [ SEEK ]   CLEC2A [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)387836
GTEX Portal (Tissue expression)CLEC2A
Human Protein AtlasENSG00000188393-CLEC2A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6UVW9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6UVW9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6UVW9
Splice isoforms : SwissVarQ6UVW9
PhosPhoSitePlusQ6UVW9
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link_sf    CTDL_fold    NKR-like_CTLD   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC2A
DMDM Disease mutations387836
Blocks (Seattle)CLEC2A
PDB (RSDB)4IOP   
PDB Europe4IOP   
PDB (PDBSum)4IOP   
PDB (IMB)4IOP   
Structural Biology KnowledgeBase4IOP   
SCOP (Structural Classification of Proteins)4IOP   
CATH (Classification of proteins structures)4IOP   
SuperfamilyQ6UVW9
Human Protein Atlas [tissue]ENSG00000188393-CLEC2A [tissue]
Peptide AtlasQ6UVW9
HPRD16720
IPIIPI00914678   IPI00398946   
Protein Interaction databases
DIP (DOE-UCLA)Q6UVW9
IntAct (EBI)Q6UVW9
FunCoupENSG00000188393
BioGRIDCLEC2A
STRING (EMBL)CLEC2A
ZODIACCLEC2A
Ontologies - Pathways
QuickGOQ6UVW9
Ontology : AmiGOprotein binding  plasma membrane  integral component of membrane  carbohydrate binding  natural killer cell mediated cytotoxicity  protein homodimerization activity  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of membrane  carbohydrate binding  natural killer cell mediated cytotoxicity  protein homodimerization activity  
NDEx NetworkCLEC2A
Atlas of Cancer Signalling NetworkCLEC2A
Wikipedia pathwaysCLEC2A
Orthology - Evolution
OrthoDB387836
GeneTree (enSembl)ENSG00000188393
Phylogenetic Trees/Animal Genes : TreeFamCLEC2A
HOGENOMQ6UVW9
Homologs : HomoloGeneCLEC2A
Homology/Alignments : Family Browser (UCSC)CLEC2A
Gene fusions - Rearrangements
Fusion : MitelmanPAWR/CLEC2A [12q21.2/12p13.31]  [t(12;12)(p13;q21)]  
Fusion PortalPAWR 12q21.2 CLEC2A 12p13.31 BRCA
Fusion : QuiverCLEC2A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC2A
dbVarCLEC2A
ClinVarCLEC2A
1000_GenomesCLEC2A 
Exome Variant ServerCLEC2A
ExAC (Exome Aggregation Consortium)ENSG00000188393
GNOMAD BrowserENSG00000188393
Varsome BrowserCLEC2A
Genetic variants : HAPMAP387836
Genomic Variants (DGV)CLEC2A [DGVbeta]
DECIPHERCLEC2A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC2A 
Mutations
ICGC Data PortalCLEC2A 
TCGA Data PortalCLEC2A 
Broad Tumor PortalCLEC2A
OASIS PortalCLEC2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC2A  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCLEC2A
Mutations and Diseases : HGMDCLEC2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC2A
DgiDB (Drug Gene Interaction Database)CLEC2A
DoCM (Curated mutations)CLEC2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC2A (select a term)
intoGenCLEC2A
Cancer3DCLEC2A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612087   
Orphanet
DisGeNETCLEC2A
MedgenCLEC2A
Genetic Testing Registry CLEC2A
NextProtQ6UVW9 [Medical]
TSGene387836
GENETestsCLEC2A
Target ValidationCLEC2A
Huge Navigator CLEC2A [HugePedia]
snp3D : Map Gene to Disease387836
BioCentury BCIQCLEC2A
ClinGenCLEC2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD387836
Chemical/Pharm GKB GenePA142672099
Clinical trialCLEC2A
Miscellaneous
canSAR (ICR)CLEC2A (select the gene name)
DataMed IndexCLEC2A
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC2A
EVEXCLEC2A
GoPubMedCLEC2A
iHOPCLEC2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Nov 13 17:37:40 CET 2019
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