Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
INPE5792,KACL,PILAR,UNQ5792
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 387836
MIM: 612087
HGNC: 24191
Ensembl: ENSG00000188393
Variants:
dbSNP: 387836
ClinVar: 387836
TCGA: ENSG00000188393
COSMIC: CLEC2A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000188393 | ENST00000339766 | Q6UVW9 |
| ENSG00000188393 | ENST00000455827 | Q6UVW9 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31901221 | 2020 | A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade. | 12 |
| 32061658 | 2020 | NK Cell and Fibroblast-Mediated Regulation of Skin Squamous Cell Carcinoma Invasion by CLEC2A Is Compromised in Xeroderma Pigmentosum. | 13 |
| 31901221 | 2020 | A Comprehensive Tyrosine Phosphoproteomic Analysis Reveals Novel Components of the Platelet CLEC-2 Signaling Cascade. | 12 |
| 32061658 | 2020 | NK Cell and Fibroblast-Mediated Regulation of Skin Squamous Cell Carcinoma Invasion by CLEC2A Is Compromised in Xeroderma Pigmentosum. | 13 |
| 27960039 | 2017 | Physiologic and pathophysiologic roles of interaction between C-type lectin-like receptor 2 and podoplanin: partners from in utero to adulthood. | 32 |
| 27960039 | 2017 | Physiologic and pathophysiologic roles of interaction between C-type lectin-like receptor 2 and podoplanin: partners from in utero to adulthood. | 32 |
| 25510854 | 2015 | Key residues at the membrane-distal surface of KACL, but not glycosylation, determine the functional interaction of the keratinocyte-specific C-type lectin-like receptor KACL with its high-affinity receptor NKp65. | 2 |
| 26416420 | 2015 | PDGF upregulates CLEC-2 to induce T regulatory cells. | 24 |
| 25510854 | 2015 | Key residues at the membrane-distal surface of KACL, but not glycosylation, determine the functional interaction of the keratinocyte-specific C-type lectin-like receptor KACL with its high-affinity receptor NKp65. | 2 |
| 26416420 | 2015 | PDGF upregulates CLEC-2 to induce T regulatory cells. | 24 |
| 25150298 | 2014 | CLEC-2 expression is maintained on activated platelets and on platelet microparticles. | 53 |
| 25150298 | 2014 | CLEC-2 expression is maintained on activated platelets and on platelet microparticles. | 53 |
| 20194751 | 2010 | Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes. | 26 |
| 20194751 | 2010 | Interaction of C-type lectin-like receptors NKp65 and KACL facilitates dedicated immune recognition of human keratinocytes. | 26 |
| 19630798 | 2009 | Novel interactions in platelet biology: CLEC-2/podoplanin and laminin/GPVI. | 17 |
Citation
Dessen P
CLEC2A (C-type lectin domain family 2 member A)
Atlas Genet Cytogenet Oncol Haematol. 2010-01-01
Online version: http://atlasgeneticsoncology.org/gene/51249/clec2a
