CLNK (cytokine dependent hematopoietic cell linker)

2014-11-01  

Identity

HGNC
LOCATION
4p16.1
LOCUSID
ALIAS
MIST
FUSION GENES

Other Information

Locus ID:

NCBI: 116449
MIM: 611434
HGNC: 17438
Ensembl: ENSG00000109684

Variants:

dbSNP: 116449
ClinVar: 116449
TCGA: ENSG00000109684
COSMIC: CLNK

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000109684ENST00000226951Q7Z7G1
ENSG00000109684ENST00000442825A0A0A0MSJ4
ENSG00000109684ENST00000507719Q7Z7G1
ENSG00000109684ENST00000515667D6RJB9

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA164712445AntihypertensivesChemicalClinicalAnnotation, VariantAnnotationassociatedPD28222112
PA444552HypertensionDiseaseClinicalAnnotation, VariantAnnotationassociatedPD28222112

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
189876182009Screening for replication of genome-wide SNP associations in sporadic ALS.14
255916612015Genetic variations in the CLNK gene and ZNF518B gene are associated with gout in case-control sample sets.7
264383872016WDR1 and CLNK gene polymorphisms correlate with serum glucose and high-density lipoprotein levels in Tibetan gout patients.0

Citation

Dessen P

CLNK (cytokine dependent hematopoietic cell linker)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/61897/clnk