CLPTM1L (CLPTM1 like)

2003-08-01  

Identity

HGNC
CLPTM1L
LOCATION
5p15.33
LOCUSID
81037
ALIAS
CRR9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 81037
MIM: 612585
HGNC: 24308
Ensembl: ENSG00000049656

Variants:

dbSNP: 81037
ClinVar: 81037
TCGA: ENSG00000049656
COSMIC: CLPTM1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000049656ENST00000320895Q96KA5
ENSG00000049656ENST00000507807G5E9Z2
ENSG00000049656ENST00000630539G5E9Z2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
191517172009Sequence variants at the TERT-CLPTM1L locus associate with many cancer types.268
201012432010A genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.261
189787902008Lung cancer susceptibility locus at 5p15.33.257
189787902008Lung cancer susceptibility locus at 5p15.33.257
189787872008Common 5p15.33 and 6p21.33 variants influence lung cancer risk.243
220375532011A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancer.177
205438472010Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer.147
195783632009New common variants affecting susceptibility to basal cell carcinoma.135
205480212010Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium.86
207004382010The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia.82

Citation

Dessen P

CLPTM1L (CLPTM1 like)

Atlas Genet Cytogenet Oncol Haematol. 2003-08-01

Online version: http://atlasgeneticsoncology.org/gene/40152/clptm1l