CMKLR1 (chemerin chemokine-like receptor 1)

2014-08-01  

Identity

HGNC
LOCATION
12q23.3
LOCUSID
ALIAS
CHEMERINR,ChemR23,DEZ,RVER1
FUSION GENES

Other Information

Locus ID:

NCBI: 1240
MIM: 602351
HGNC: 2121
Ensembl: ENSG00000174600

Variants:

dbSNP: 1240
ClinVar: 1240
TCGA: ENSG00000174600
COSMIC: CMKLR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174600ENST00000312143Q99788
ENSG00000174600ENST00000412676Q99788
ENSG00000174600ENST00000549466F8VSC8
ENSG00000174600ENST00000550402Q99788
ENSG00000174600ENST00000550573F8VYN7
ENSG00000174600ENST00000552995Q99788

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
157532052005Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1.277
199066412010Resolvin E1 receptor activation signals phosphorylation and phagocytosis.95
200449792010Identification of chemerin receptor (ChemR23) in human endothelial cells: chemerin-induced endothelial angiogenesis.88
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
211928182010Human articular chondrocytes express ChemR23 and chemerin; ChemR23 promotes inflammatory signalling upon binding the ligand chemerin(21-157).37
214830232011Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy.35
217156842011Regulation of chemerin chemoattractant and antibacterial activity by human cysteine cathepsins.31
226107472012Chemerin: a potential endocrine link between obesity and type 2 diabetes.29
256370172015ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.29
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27

Citation

Dessen P

CMKLR1 (chemerin chemokine-like receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54222/cmklr1