CMTM1 (CKLF like MARVEL transmembrane domain containing 1)

2015-11-01  

Identity

HGNC
CMTM1
LOCATION
16q21
LOCUSID
113540
ALIAS
CKLFH,CKLFH1,CKLFSF1

Other Information

Locus ID:

NCBI: 113540
MIM: 607884
HGNC: 19172
Ensembl: ENSG00000089505

Variants:

dbSNP: 113540
ClinVar: 113540
TCGA: ENSG00000089505
COSMIC: CMTM1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089505ENST00000328020E9PAX0
ENSG00000089505ENST00000332695Q8IZ96
ENSG00000089505ENST00000333001Q8IZ96
ENSG00000089505ENST00000336328Q8IZ96
ENSG00000089505ENST00000379500Q8IZ96
ENSG00000089505ENST00000457188Q8IZ96
ENSG00000089505ENST00000465057H0YEC2
ENSG00000089505ENST00000479381H0YEC2
ENSG00000089505ENST00000528324Q8IZ96
ENSG00000089505ENST00000528441H0YEC2
ENSG00000089505ENST00000528484Q8IZ96
ENSG00000089505ENST00000529386Q8IZ96
ENSG00000089505ENST00000529506A0A0A0MTE4
ENSG00000089505ENST00000530141H0YEC2
ENSG00000089505ENST00000531885Q8IZ96
ENSG00000089505ENST00000533078Q8IZ96
ENSG00000089505ENST00000533666Q8IZ96
ENSG00000089505ENST00000533915Q8IZ96
ENSG00000089505ENST00000533953E9PIL3
ENSG00000089505ENST00000534143H0YEC2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
127821302003Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation.31
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
151477282004Molecular cloning and characterization of chemokine-like factor super family member 1 (CKLFSF1), a novel human gene with at least 23 alternative splicing isoforms in testis tissue.9
259311112015Systematic investigation of CMTM family genes suggests relevance to glioblastoma pathogenesis and CMTM1 and CMTM3 as priority targets.5
281297752017CMTM1_v17 is associated with chemotherapy resistance and poor prognosis in non-small cell lung cancer.3
251753862014CMTM1_v17 is a novel potential therapeutic target in breast cancer.2
157780922005A functional promoter region of the CKLFSF2 gene is located in the last intron/exon region of the upstream CKLFSF1 gene.1

Citation

Dessen P

CMTM1 (CKLF like MARVEL transmembrane domain containing 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-11-01

Online version: http://atlasgeneticsoncology.org/gene/55507/cmtm1