CMTR1 (cap methyltransferase 1)

2014-08-01  

Identity

HGNC
LOCATION
6p21.2
LOCUSID
ALIAS
FTSJD2,KIAA0082,MTr1,hMTr1
FUSION GENES

Other Information

Locus ID:

NCBI: 23070
MIM: 616189
HGNC: 21077
Ensembl: ENSG00000137200

Variants:

dbSNP: 23070
ClinVar: 23070
TCGA: ENSG00000137200
COSMIC: CMTR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137200ENST00000373451Q8N1G2
ENSG00000137200ENST00000455891Q5T7F5
ENSG00000137200ENST00000457419H0Y4T0
ENSG00000137200ENST00000475364H0YCQ1

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
207133562010Characterization of hMTr1, a human Cap1 2'-O-ribose methyltransferase.36
244024422014Structural analysis of human 2'-O-ribose methyltransferases involved in mRNA cap structure formation.23
185331092008The human interferon-regulated ISG95 protein interacts with RNA polymerase II and shows methyltransferase activity.12
289716292017Regulation and function of CMTR1-dependent mRNA cap methylation.5
303970982018Human RNA cap1 methyltransferase CMTr1 cooperates with RNA helicase DHX15 to modify RNAs with highly structured 5' termini.2

Citation

Dessen P

CMTR1 (cap methyltransferase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54223/cmtr1