Identity
HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
CTS2,EDM1,EPD1,MED,PSACH,THBS5,TSP5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1311
MIM: 600310
HGNC: 2227
Ensembl: ENSG00000105664
Variants:
dbSNP: 1311
ClinVar: 1311
TCGA: ENSG00000105664
COSMIC: COMP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105664 | ENST00000222271 | P49747 |
| ENSG00000105664 | ENST00000425807 | P49747 |
| ENSG00000105664 | ENST00000542601 | G3XAP6 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38479555 | 2024 | COMP promotes pancreatic fibrosis by activating pancreatic stellate cells through CD36-ERK/AKT signaling pathways. | 1 |
| 38528617 | 2024 | Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration. | 1 |
| 38479555 | 2024 | COMP promotes pancreatic fibrosis by activating pancreatic stellate cells through CD36-ERK/AKT signaling pathways. | 1 |
| 38528617 | 2024 | Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration. | 1 |
| 37207219 | 2023 | Expression of Cartilage Oligomeric Matrix Protein in colorectal cancer is an adverse prognostic factor and correlates negatively with infiltrating immune cells and PD-L1 expression. | 2 |
| 37461830 | 2023 | Functional characterization of a rare pathogenic variant c.875G > A, p.(Cys292Tyr) in COMP. | 0 |
| 37556859 | 2023 | A preliminary study on the effect of loaded and unloaded exercise on N-propeptide of type II collagen and serum cartilage oligomeric matrix protein activity of articular cartilage in healthy young adults. | 0 |
| 37838792 | 2023 | Cartilage oligomeric matrix protein overexpression is an independent poor prognostic indicator in patients with intrahepatic cholangiocarcinoma. | 0 |
| 37207219 | 2023 | Expression of Cartilage Oligomeric Matrix Protein in colorectal cancer is an adverse prognostic factor and correlates negatively with infiltrating immune cells and PD-L1 expression. | 2 |
| 37461830 | 2023 | Functional characterization of a rare pathogenic variant c.875G > A, p.(Cys292Tyr) in COMP. | 0 |
| 37556859 | 2023 | A preliminary study on the effect of loaded and unloaded exercise on N-propeptide of type II collagen and serum cartilage oligomeric matrix protein activity of articular cartilage in healthy young adults. | 0 |
| 37838792 | 2023 | Cartilage oligomeric matrix protein overexpression is an independent poor prognostic indicator in patients with intrahepatic cholangiocarcinoma. | 0 |
| 34709441 | 2022 | Clinical, Biochemical, Radiological, Genetic and Therapeutic Analysis of Patients with COMP Gene Variants. | 2 |
| 35088463 | 2022 | Expression of cartilage oligomeric matrix protein (COMP) associates with capsular invasion in salivary gland pleomorphic adenoma. | 0 |
| 35468843 | 2022 | Duchenne muscular dystrophy trajectory in R-DMDdel52 preclinical rat model identifies COMP as biomarker of fibrosis. | 14 |
Citation
Dessen P
COMP (cartilage oligomeric matrix protein)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46113/comp
