COPE (COPI coat complex subunit epsilon)

2008-07-01  

Identity

HGNC
LOCATION
19p13.11
LOCUSID
ALIAS
epsilon-COP
FUSION GENES

Other Information

Locus ID:

NCBI: 11316
MIM: 606942
HGNC: 2234
Ensembl: ENSG00000105669

Variants:

dbSNP: 11316
ClinVar: 11316
TCGA: ENSG00000105669
COSMIC: COPE

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000105669ENST00000262812O14579
ENSG00000105669ENST00000349893O14579
ENSG00000105669ENST00000351079O14579
ENSG00000105669ENST00000593827M0R061
ENSG00000105669ENST00000600932M0QXB4

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Asparagine N-linked glycosylationREACTOMER-HSA-446203
Transport to the Golgi and subsequent modificationREACTOMER-HSA-948021
ER to Golgi Anterograde TransportREACTOMER-HSA-199977
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
COPI-mediated anterograde transportREACTOMER-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Golgi-to-ER retrograde transportREACTOMER-HSA-8856688
COPI-dependent Golgi-to-ER retrograde trafficREACTOMER-HSA-6811434

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
196329842009Intracellular phospholipase A1gamma (iPLA1gamma) is a novel factor involved in coat protein complex I- and Rab6-independent retrograde transport between the endoplasmic reticulum and the Golgi complex.22
177218092008Ubiquitylation of epsilon-COP by PIRH2 and regulation of the secretion of PSA.4

Citation

Dessen P

COPE (COPI coat complex subunit epsilon)

Atlas Genet Cytogenet Oncol Haematol. 2008-07-01

Online version: http://atlasgeneticsoncology.org/gene/50234/cope