Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8533
MIM: 604665
HGNC: 2239
Ensembl: ENSG00000141030
Variants:
dbSNP: 8533
ClinVar: 8533
TCGA: ENSG00000141030
COSMIC: COPS3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36451342 | 2023 | The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma. | 7 |
| 36451342 | 2023 | The COPS3-FOXO3 positive feedback loop regulates autophagy to promote cisplatin resistance in osteosarcoma. | 7 |
| 31509289 | 2019 | Knockdown of COPS3 inhibits the progress of prostate cancer through reducing phosphorylated p38 MAPK expression and impairs the epithelial-mesenchymal transition process. | 5 |
| 31509289 | 2019 | Knockdown of COPS3 inhibits the progress of prostate cancer through reducing phosphorylated p38 MAPK expression and impairs the epithelial-mesenchymal transition process. | 5 |
| 29477618 | 2018 | Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3. | 8 |
| 29970115 | 2018 | Novel oncogene COPS3 interacts with Beclin1 and Raf-1 to regulate metastasis of osteosarcoma through autophagy. | 35 |
| 29477618 | 2018 | Overexpression of COPS3 promotes clear cell renal cell carcinoma progression via regulation of Phospho-AKT(Thr308), Cyclin D1 and Caspase-3. | 8 |
| 29970115 | 2018 | Novel oncogene COPS3 interacts with Beclin1 and Raf-1 to regulate metastasis of osteosarcoma through autophagy. | 35 |
| 28891468 | 2017 | Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex. | 10 |
| 28891468 | 2017 | Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex. | 10 |
| 22237956 | 2012 | Inhibition of Csn3 expression induces growth arrest and apoptosis of hepatocellular carcinoma cells. | 14 |
| 22237956 | 2012 | Inhibition of Csn3 expression induces growth arrest and apoptosis of hepatocellular carcinoma cells. | 14 |
| 21436869 | 2011 | RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells. | 7 |
| 21436869 | 2011 | RNAi-mediated COPS3 gene silencing inhibits metastasis of osteogenic sarcoma cells. | 7 |
Citation
Dessen P
COPS3 (COP9 signalosome subunit 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/46656/cops3
