CPEB2 (cytoplasmic polyadenylation element binding protein 2)

2015-03-01  

Identity

HGNC
CPEB2
LOCATION
4p15.32
LOCUSID
132864
ALIAS
CPE-BP2,CPEB-2,hCPEB-2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 132864
MIM: 610605
HGNC: 21745
Ensembl: ENSG00000137449

Variants:

dbSNP: 132864
ClinVar: 132864
TCGA: ENSG00000137449
COSMIC: CPEB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137449ENST00000345451Q7Z5Q1
ENSG00000137449ENST00000382395Q7Z5Q1
ENSG00000137449ENST00000382401Q7Z5Q1
ENSG00000137449ENST00000442003Q7Z5Q1
ENSG00000137449ENST00000507071Q7Z5Q1
ENSG00000137449ENST00000509684H0Y9D9
ENSG00000137449ENST00000538197Q7Z5Q1

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Dorso-ventral axis formationKEGGko04320
Progesterone-mediated oocyte maturationKEGGko04914
Dorso-ventral axis formationKEGGhsa04320
Progesterone-mediated oocyte maturationKEGGhsa04914
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114

References

Pubmed IDYearTitleCitations
283024872017TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis.25
283582632017LncRNA CCAT1 modulates the sensitivity of paclitaxel in nasopharynx cancers cells via miR-181a/CPEB2 axis.22
126726602003CPEB2, a novel putative translational regulator in mouse haploid germ cells.17
284604692017Identification of microRNA 885-5p as a novel regulator of tumor metastasis by targeting CPEB2 in colorectal cancer.14
263041152015The Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer.11
263981952015Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle.4
311386012019Serine/Arginine-Rich Splicing Factor 3 Modulates the Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2.1
311859862019Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells.1

Citation

Dessen P

CPEB2 (cytoplasmic polyadenylation element binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55640/cpeb2