CPQ (carboxypeptidase Q)

2014-08-01  

Identity

HGNC
CPQ
LOCATION
8q22.1
LOCUSID
10404
ALIAS
LDP,PGCP
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10404
MIM: 618754
HGNC: 16910
Ensembl: ENSG00000104324

Variants:

dbSNP: 10404
ClinVar: 10404
TCGA: ENSG00000104324
COSMIC: CPQ

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000104324ENST00000220763Q9Y646
ENSG00000104324ENST00000220763A0A024R9B8
ENSG00000104324ENST00000517742E5RJA8
ENSG00000104324ENST00000519484E5RJP8
ENSG00000104324ENST00000519900E5RJZ7
ENSG00000104324ENST00000521142E5RH35
ENSG00000104324ENST00000522617H0YBB7

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
208024792010Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1.100
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
202019262010Human variation in alcohol response is influenced by variation in neuronal signaling genes.45
278063302016Plasma glutamate carboxypeptidase is a negative regulator in liver cancer metastasis.4
291962552018Hypermethylation of PGCP gene is associated with human bronchial epithelial cells immortalization.0

Citation

Dessen P

CPQ (carboxypeptidase Q)

Atlas Genet Cytogenet Oncol Haematol. 2014-08-01

Online version: http://atlasgeneticsoncology.org/gene/54234/cpq