Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8738
MIM: 603454
HGNC: 2340
Ensembl: ENSG00000169372
Variants:
dbSNP: 8738
ClinVar: 8738
TCGA: ENSG00000169372
COSMIC: CRADD
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33647455 | 2021 | CRADD and USP44 mutations in intellectual disability, mild lissencephaly, brain atrophy, developmental delay, strabismus, behavioural problems and skeletal anomalies. | 5 |
| 33647455 | 2021 | CRADD and USP44 mutations in intellectual disability, mild lissencephaly, brain atrophy, developmental delay, strabismus, behavioural problems and skeletal anomalies. | 5 |
| 30914828 | 2019 | Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population. | 10 |
| 30914828 | 2019 | Phenotypic spectrum associated with a CRADD founder variant underlying frontotemporal predominant pachygyria in the Finnish population. | 10 |
| 28686357 | 2017 | Homozygous null variant in CRADD, encoding an adaptor protein that mediates apoptosis, is associated with lissencephaly. | 11 |
| 28686357 | 2017 | Homozygous null variant in CRADD, encoding an adaptor protein that mediates apoptosis, is associated with lissencephaly. | 11 |
| 27606466 | 2016 | RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. | 3 |
| 27773430 | 2016 | Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant. | 29 |
| 27606466 | 2016 | RAIDD Mediates TLR3 and IRF7 Driven Type I Interferon Production. | 3 |
| 27773430 | 2016 | Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant. | 29 |
| 24958727 | 2014 | The adaptor CRADD/RAIDD controls activation of endothelial cells by proinflammatory stimuli. | 6 |
| 24958727 | 2014 | The adaptor CRADD/RAIDD controls activation of endothelial cells by proinflammatory stimuli. | 6 |
| 22279524 | 2012 | Genetic mapping and exome sequencing identify variants associated with five novel diseases. | 145 |
| 22279524 | 2012 | Genetic mapping and exome sequencing identify variants associated with five novel diseases. | 145 |
| 20208132 | 2010 | PIDDosome expression and the role of caspase-2 activation for chemotherapy-induced apoptosis in RCCs. | 6 |
Citation
Dessen P
CRADD (CASP2 and RIPK1 domain containing adaptor with death domain)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/40144/cradd
