CREBZF (CREB/ATF bZIP transcription factor)

2014-11-01  

Identity

HGNC
LOCATION
11q14.1
LOCUSID
ALIAS
SMILE,ZF
FUSION GENES

Other Information

Locus ID:

NCBI: 58487
MIM: 606444
HGNC: 24905
Ensembl: ENSG00000137504

Variants:

dbSNP: 58487
ClinVar: 58487
TCGA: ENSG00000137504
COSMIC: CREBZF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137504ENST00000260058J3KN20
ENSG00000137504ENST00000490820Q9NS37
ENSG00000137504ENST00000525639E9PIM0
ENSG00000137504ENST00000527447Q9NS37
ENSG00000137504ENST00000527529H0YDC7
ENSG00000137504ENST00000534224E9PRP7

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
196901662009Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.20
186570492008SMILE, a new orphan nuclear receptor SHP-interacting protein, regulates SHP-repressed estrogen receptor transactivation.19
162824712005The neuronal host cell factor-binding protein Zhangfei inhibits herpes simplex virus replication.17
163434882006Cooperative interaction of Zhangfei and ATF4 in transactivation of the cyclic AMP response element.17
157055662005Zhangfei is a potent and specific inhibitor of the host cell factor-binding transcription factor Luman.15
219949472011Curcumin differentially regulates endoplasmic reticulum stress through transcriptional corepressor SMILE (small heterodimer partner-interacting leucine zipper protein)-mediated inhibition of CREBH (cAMP responsive element-binding protein H).15
229830082012The transcription factor CREBZF is a novel positive regulator of p53.13
242653172014Ursodeoxycholic acid inhibits liver X receptor α-mediated hepatic lipogenesis via induction of the nuclear corepressor SMILE.12
216036542011The involvement of SMILE/TMTC3 in endoplasmic reticulum stress response.11
227982062012Mechanism for the induction of cell death in ONS-76 medulloblastoma cells by Zhangfei/CREB-ZF.10

Citation

Dessen P

CREBZF (CREB/ATF bZIP transcription factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62082/crebzf