Identity
HGNC
LOCATION
6p12.3
LOCUSID
ALIAS
Aeg2,CRISP-3,CRS3,SGP28,dJ442L6.3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10321
MIM: 618062
HGNC: 16904
Ensembl: ENSG00000096006
Variants:
dbSNP: 10321
ClinVar: 10321
TCGA: ENSG00000096006
COSMIC: CRISP3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000096006 | ENST00000263045 | P54108 |
| ENSG00000096006 | ENST00000354620 | I3L0A1 |
| ENSG00000096006 | ENST00000371159 | J3KPA1 |
| ENSG00000096006 | ENST00000433368 | P54108 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30354034 | 2019 | Cysteine-rich secretory protein 3: inflammation role in adult varicocoele. | 5 |
| 30609035 | 2019 | Low expression of CRISP3 predicts a favorable prognosis in patients with mammary carcinoma. | 10 |
| 30354034 | 2019 | Cysteine-rich secretory protein 3: inflammation role in adult varicocoele. | 5 |
| 30609035 | 2019 | Low expression of CRISP3 predicts a favorable prognosis in patients with mammary carcinoma. | 10 |
| 26369530 | 2016 | Cysteine-rich secretory protein 3 plays a role in prostate cancer cell invasion and affects expression of PSA and ANXA1. | 5 |
| 26369530 | 2016 | Cysteine-rich secretory protein 3 plays a role in prostate cancer cell invasion and affects expression of PSA and ANXA1. | 5 |
| 25715794 | 2015 | Endometrial CRISP3 is regulated throughout the mouse estrous and human menstrual cycle and facilitates adhesion and proliferation of endometrial epithelial cells. | 9 |
| 25715794 | 2015 | Endometrial CRISP3 is regulated throughout the mouse estrous and human menstrual cycle and facilitates adhesion and proliferation of endometrial epithelial cells. | 9 |
| 24978310 | 2014 | Cysteine-rich secretory protein 3 inhibits hepatitis C virus at the initial phase of infection. | 1 |
| 24978310 | 2014 | Cysteine-rich secretory protein 3 inhibits hepatitis C virus at the initial phase of infection. | 1 |
| 23196798 | 2013 | Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical recurrence. | 14 |
| 23375721 | 2013 | Mapping of the binding sites involved in PSP94-CRISP-3 interaction by molecular dissection of the complex. | 3 |
| 23196798 | 2013 | Cysteine-rich secretory protein 3 overexpression is linked to a subset of PTEN-deleted ERG fusion-positive prostate cancers with early biochemical recurrence. | 14 |
| 23375721 | 2013 | Mapping of the binding sites involved in PSP94-CRISP-3 interaction by molecular dissection of the complex. | 3 |
| 22993349 | 2012 | The expression of β-microseminoprotein but not CRISP3 is reduced in ovarian cancer and correlates to survival. | 3 |
Citation
Dessen P
CRISP3 (cysteine rich secretory protein 3)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46180/crisp3
