Identity
HGNC
LOCATION
22q13.1
LOCUSID
ALIAS
CKIe,CKIepsilon,HCKIE
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1454
MIM: 600863
HGNC: 2453
Ensembl: ENSG00000213923
Variants:
dbSNP: 1454
ClinVar: 1454
TCGA: ENSG00000213923
COSMIC: CSNK1E
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444460 | Heroin Dependence | Disease | ClinicalAnnotation | associated | PD | ||
| PA452619 | heroin | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37787983 | 2023 | CK1ε drives osteogenic differentiation of bone marrow mesenchymal stem cells via activating Wnt/β-catenin pathway. | 0 |
| 37787983 | 2023 | CK1ε drives osteogenic differentiation of bone marrow mesenchymal stem cells via activating Wnt/β-catenin pathway. | 0 |
| 32175635 | 2020 | Casein kinase 1 epsilon facilitates cartilage destruction in osteoarthritis through JNK pathway. | 5 |
| 32321936 | 2020 | CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1. | 5 |
| 32871831 | 2020 | Cytoplasmic CK1ε Protein Expression Is Correlated With Distant Metastasis and Survival in Patients With Melanoma. | 1 |
| 32888647 | 2020 | The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt signaling. | 2 |
| 32899434 | 2020 | Novel Insights into the Biochemical Mechanism of CK1ε and its Functional Interplay with DDX3X. | 0 |
| 32175635 | 2020 | Casein kinase 1 epsilon facilitates cartilage destruction in osteoarthritis through JNK pathway. | 5 |
| 32321936 | 2020 | CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1. | 5 |
| 32871831 | 2020 | Cytoplasmic CK1ε Protein Expression Is Correlated With Distant Metastasis and Survival in Patients With Melanoma. | 1 |
| 32888647 | 2020 | The Daple-CK1ε complex regulates Dvl2 phosphorylation and canonical Wnt signaling. | 2 |
| 32899434 | 2020 | Novel Insights into the Biochemical Mechanism of CK1ε and its Functional Interplay with DDX3X. | 0 |
| 30488659 | 2019 | A de novo pathogenic CSNK1E mutation identified by exome sequencing in family trios with epileptic encephalopathy. | 6 |
| 31000703 | 2019 | Dishevelled-3 conformation dynamics analyzed by FRET-based biosensors reveals a key role of casein kinase 1. | 10 |
| 31235588 | 2019 | Long noncoding RNA LINC00673-v4 promotes aggressiveness of lung adenocarcinoma via activating WNT/β-catenin signaling. | 56 |
Citation
Dessen P
CSNK1E (casein kinase 1 epsilon)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/40170/csnk1e
