Atlas of Genetics and Cytogenetics in Oncology and Haematology

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CSNK1G3 (casein kinase 1 gamma 3)

Identity

Alias_namescasein kinase 1, gamma 3
Other aliasCKI-gamma 3
CSNK1G3L
HGNC (Hugo) CSNK1G3
LocusID (NCBI) 1456
Atlas_Id 43220
Location 5q23.2  [Link to chromosome band 5q23]
Location_base_pair Starts at 123545417 and ends at 123617044 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CSNK1G3 (5q23.2) / CSNK1G3 (5q23.2)CSNK1G3 (5q23.2) / HTN3 (4q13.3)GABPB1 (15q21.2) / CSNK1G3 (5q23.2)
GABPB1 15q21.2 / CSNK1G3 5q23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;15)(q23;q21) GABPB1/CSNK1G3

External links

Nomenclature
HGNC (Hugo)CSNK1G3   2456
Cards
Entrez_Gene (NCBI)CSNK1G3  1456  casein kinase 1 gamma 3
AliasesCKI-gamma; CSNK1G3L
GeneCards (Weizmann)CSNK1G3
Ensembl hg19 (Hinxton)ENSG00000151292 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151292 [Gene_View]  ENSG00000151292 [Sequence]  chr5:123545417-123617044 [Contig_View]  CSNK1G3 [Vega]
ICGC DataPortalENSG00000151292
TCGA cBioPortalCSNK1G3
AceView (NCBI)CSNK1G3
Genatlas (Paris)CSNK1G3
WikiGenes1456
SOURCE (Princeton)CSNK1G3
Genetics Home Reference (NIH)CSNK1G3
Genomic and cartography
GoldenPath hg38 (UCSC)CSNK1G3  -     chr5:123545417-123617044 +  5q23.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CSNK1G3  -     5q23.2   [Description]    (hg19-Feb_2009)
GoldenPathCSNK1G3 - 5q23.2 [CytoView hg19]  CSNK1G3 - 5q23.2 [CytoView hg38]
ImmunoBaseENSG00000151292
Mapping of homologs : NCBICSNK1G3 [Mapview hg19]  CSNK1G3 [Mapview hg38]
OMIM604253   
Gene and transcription
Genbank (Entrez)AA989359 AF049089 AF049090 AK289405 AK299739
RefSeq transcript (Entrez)NM_001031812 NM_001044722 NM_001044723 NM_001270572 NM_001270573 NM_001270574 NM_001364140 NM_001364141 NM_001364143 NM_001364144 NM_001364145 NM_001364146 NM_001364147 NM_001364148 NM_001364149 NM_001364150 NM_004384
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CSNK1G3
Cluster EST : UnigeneHs.741716 [ NCBI ]
CGAP (NCI)Hs.741716
Alternative Splicing GalleryENSG00000151292
Gene ExpressionCSNK1G3 [ NCBI-GEO ]   CSNK1G3 [ EBI - ARRAY_EXPRESS ]   CSNK1G3 [ SEEK ]   CSNK1G3 [ MEM ]
Gene Expression Viewer (FireBrowse)CSNK1G3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1456
GTEX Portal (Tissue expression)CSNK1G3
Human Protein AtlasENSG00000151292-CSNK1G3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6M4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6M4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6M4
Splice isoforms : SwissVarQ9Y6M4
PhosPhoSitePlusQ9Y6M4
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Casein_kinase-1_gamma_C    Kinase-like_dom_sf    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)CK1gamma_C (PF12605)    Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam12605    pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)CSNK1G3
DMDM Disease mutations1456
Blocks (Seattle)CSNK1G3
PDB (RSDB)2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
PDB Europe2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
PDB (PDBSum)2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
PDB (IMB)2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
Structural Biology KnowledgeBase2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
SCOP (Structural Classification of Proteins)2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
CATH (Classification of proteins structures)2CHL    2IZR    2IZS    2IZT    2IZU    4G16    4G17    4HGL    4HGS   
SuperfamilyQ9Y6M4
Human Protein Atlas [tissue]ENSG00000151292-CSNK1G3 [tissue]
Peptide AtlasQ9Y6M4
HPRD05034
IPIIPI00181294   IPI00218437   IPI00941996   IPI00788259   IPI00410228   IPI00965975   IPI00964868   IPI00984518   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6M4
IntAct (EBI)Q9Y6M4
FunCoupENSG00000151292
BioGRIDCSNK1G3
STRING (EMBL)CSNK1G3
ZODIACCSNK1G3
Ontologies - Pathways
QuickGOQ9Y6M4
Ontology : AmiGOprotein kinase activity  protein serine/threonine kinase activity  protein serine/threonine kinase activity  ATP binding  nucleus  cytoplasm  plasma membrane  cellular protein modification process  endocytosis  signal transduction  Wnt signaling pathway  peptidyl-serine phosphorylation  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  positive regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBIprotein kinase activity  protein serine/threonine kinase activity  protein serine/threonine kinase activity  ATP binding  nucleus  cytoplasm  plasma membrane  cellular protein modification process  endocytosis  signal transduction  Wnt signaling pathway  peptidyl-serine phosphorylation  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  positive regulation of canonical Wnt signaling pathway  
Pathways : KEGGHedgehog signaling pathway   
NDEx NetworkCSNK1G3
Atlas of Cancer Signalling NetworkCSNK1G3
Wikipedia pathwaysCSNK1G3
Orthology - Evolution
OrthoDB1456
GeneTree (enSembl)ENSG00000151292
Phylogenetic Trees/Animal Genes : TreeFamCSNK1G3
HOGENOMQ9Y6M4
Homologs : HomoloGeneCSNK1G3
Homology/Alignments : Family Browser (UCSC)CSNK1G3
Gene fusions - Rearrangements
Fusion : MitelmanGABPB1/CSNK1G3 [15q21.2/5q23.2]  [t(5;15)(q23;q21)]  
Fusion PortalGABPB1 15q21.2 CSNK1G3 5q23.2 PRAD
Fusion : QuiverCSNK1G3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCSNK1G3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CSNK1G3
dbVarCSNK1G3
ClinVarCSNK1G3
1000_GenomesCSNK1G3 
Exome Variant ServerCSNK1G3
ExAC (Exome Aggregation Consortium)ENSG00000151292
GNOMAD BrowserENSG00000151292
Varsome BrowserCSNK1G3
Genetic variants : HAPMAP1456
Genomic Variants (DGV)CSNK1G3 [DGVbeta]
DECIPHERCSNK1G3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCSNK1G3 
Mutations
ICGC Data PortalCSNK1G3 
TCGA Data PortalCSNK1G3 
Broad Tumor PortalCSNK1G3
OASIS PortalCSNK1G3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCSNK1G3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCSNK1G3
Mutations and Diseases : HGMDCSNK1G3
intOGen PortalCSNK1G3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CSNK1G3
DgiDB (Drug Gene Interaction Database)CSNK1G3
DoCM (Curated mutations)CSNK1G3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CSNK1G3 (select a term)
intoGenCSNK1G3
Cancer3DCSNK1G3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604253   
Orphanet
DisGeNETCSNK1G3
MedgenCSNK1G3
Genetic Testing Registry CSNK1G3
NextProtQ9Y6M4 [Medical]
TSGene1456
GENETestsCSNK1G3
Target ValidationCSNK1G3
Huge Navigator CSNK1G3 [HugePedia]
snp3D : Map Gene to Disease1456
BioCentury BCIQCSNK1G3
ClinGenCSNK1G3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1456
Chemical/Pharm GKB GenePA26956
Clinical trialCSNK1G3
Miscellaneous
canSAR (ICR)CSNK1G3 (select the gene name)
DataMed IndexCSNK1G3
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCSNK1G3
EVEXCSNK1G3
GoPubMedCSNK1G3
iHOPCSNK1G3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Nov 13 17:38:55 CET 2019
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