CST2 (cystatin SA)

2014-11-01  

Identity

HGNC
LOCATION
20p11.21
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 1470
MIM: 123856
HGNC: 2474
Ensembl: ENSG00000170369

Variants:

dbSNP: 1470
ClinVar: 1470
TCGA: ENSG00000170369
COSMIC: CST2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170369ENST00000304725P09228

Expression (GTEx)

0
1
2

Pathways

PathwaySourceExternal ID
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
201983152010Association of genetic variants with hemorrhagic stroke in Japanese individuals.11
231225332013Autoimmunity and cystatin SA1 deficiency behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type 1.7
218467282011Identification of cystatin SA as a novel inhibitor of acid ceramidase.6
124136932002Salivary cystatins induce interleukin-6 expression via cell surface molecules in human gingival fibroblasts.5
198512962010Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.3
277642122016Structural Dynamics Investigation of Human Family 1 & 2 Cystatin-Cathepsin L1 Interaction: A Comparison of Binding Modes.1
313761832019A four-gene transcript score to predict metastatic-lethal progression in men treated for localized prostate cancer: Development and validation studies.1
120138242002Sac I Restriction Fragment Length Polymorphism (RFLP) related to the human CST2 gene.0
158293152005Murine monoclonal antibody which can distinguish cystatins SA1 and SA2.0

Citation

Dessen P

CST2 (cystatin SA)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62143/cst2