| Nomenclature |
|---|
| HGNC (Hugo) | CTBP1 2494 |
| Cards |
|---|
| Entrez_Gene (NCBI) | CTBP1 C-terminal binding protein 1 |
| Aliases | BARS; HADDTS |
| GeneCards (Weizmann) | CTBP1 |
| Ensembl hg19 (Hinxton) | ENSG00000159692 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000159692 [Gene_View] ENSG00000159692 [Sequence] chr4:1211445-1249990 [Contig_View] CTBP1 [Vega] |
| ICGC DataPortal | ENSG00000159692 |
| TCGA cBioPortal | CTBP1 |
| AceView (NCBI) | CTBP1 |
| Genatlas (Paris) | CTBP1 |
| SOURCE (Princeton) | CTBP1 |
| Genetics Home Reference (NIH) | CTBP1 |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | CTBP1 - chr4:1211445-1249990 - 4p16.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | CTBP1 - 4p16.3 [Description] (hg19-Feb_2009) |
| GoldenPath | CTBP1 - 4p16.3 [CytoView hg19] CTBP1 - 4p16.3 [CytoView hg38] |
| ImmunoBase | ENSG00000159692 |
| genome Data Viewer NCBI | CTBP1 [Mapview hg19] |
| OMIM | 194190 602618 617915 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF091555 AL137653 BC011655 BC053320 BC064333 |
| RefSeq transcript (Entrez) | NM_001012614 NM_001328 NM_001377186 NM_001377187 NM_001377188 NM_001377189 NM_001377190 NM_001377191 NM_001377192 NM_001377193 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | CTBP1 |
| Alternative Splicing Gallery | ENSG00000159692 |
| Gene Expression | CTBP1 [ NCBI-GEO ] CTBP1 [ EBI - ARRAY_EXPRESS ]
CTBP1 [ SEEK ] CTBP1 [ MEM ] |
| Gene Expression Viewer (FireBrowse) | CTBP1 [ Firebrowse - Broad ] |
| Genevisible | Expression of CTBP1 in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 1487 |
| GTEX Portal (Tissue expression) | CTBP1 |
| Human Protein Atlas | ENSG00000159692-CTBP1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q13363 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q13363 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q13363 |
| Splice isoforms : SwissVar | Q13363 |
| PhosPhoSitePlus | Q13363 |
| Domaine pattern : Prosite (Expaxy) | D_2_HYDROXYACID_DH_1 (PS00065) D_2_HYDROXYACID_DH_3 (PS00671) |
| Domains : Interpro (EBI) | D-isomer_2_OHA_DH_cat_dom D-isomer_DH_CS D-isomer_DH_CS1 D-isomer_DH_NAD-bd NAD(P)-bd_dom_sf |
| Domain families : Pfam (Sanger) | 2-Hacid_dh (PF00389) 2-Hacid_dh_C (PF02826) |
| Domain families : Pfam (NCBI) | pfam00389 pfam02826 |
| Conserved Domain (NCBI) | CTBP1 |
| Blocks (Seattle) | CTBP1 |
| PDB (RSDB) | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| PDB Europe | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| PDB (PDBSum) | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| PDB (IMB) | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| Structural Biology KnowledgeBase | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| SCOP (Structural Classification of Proteins) | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| CATH (Classification of proteins structures) | 1MX3 4LCE 4U6Q 4U6S 6CDF 6CDR |
| Superfamily | Q13363 |
| Human Protein Atlas [tissue] | ENSG00000159692-CTBP1 [tissue] |
| Peptide Atlas | Q13363 |
| HPRD | 04015 |
| IPI | IPI00012835 IPI00450767 IPI00966719 IPI00554626 IPI00968298 IPI00964612 IPI00964890 IPI00964078 IPI00965152 IPI00965652 IPI00965405 IPI00964334 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q13363 |
| IntAct (EBI) | Q13363 |
| BioGRID | CTBP1 |
| STRING (EMBL) | CTBP1 |
| ZODIAC | CTBP1 |
| Ontologies - Pathways |
|---|
| QuickGO | Q13363 |
| Ontology : AmiGO | negative regulation of transcription by RNA polymerase II chromatin binding transcription corepressor activity protein binding nucleus nucleus nucleoplasm nucleoplasm chromatin silencing protein phosphorylation protein C-terminus binding transcription factor binding negative regulation of cell proliferation oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor transcriptional repressor complex transcriptional repressor complex viral genome replication protein domain specific binding protein domain specific binding positive regulation of histone deacetylation negative regulation of histone acetylation identical protein binding negative regulation of transcription, DNA-templated white fat cell differentiation NAD binding regulation of cell cycle oxidation-reduction process repressing transcription factor binding negative regulation of histone H4 acetylation presynaptic active zone cytoplasmic component glutamatergic synapse GABA-ergic synapse |
| Ontology : EGO-EBI | negative regulation of transcription by RNA polymerase II chromatin binding transcription corepressor activity protein binding nucleus nucleus nucleoplasm nucleoplasm chromatin silencing protein phosphorylation protein C-terminus binding transcription factor binding negative regulation of cell proliferation oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor transcriptional repressor complex transcriptional repressor complex viral genome replication protein domain specific binding protein domain specific binding positive regulation of histone deacetylation negative regulation of histone acetylation identical protein binding negative regulation of transcription, DNA-templated white fat cell differentiation NAD binding regulation of cell cycle oxidation-reduction process repressing transcription factor binding negative regulation of histone H4 acetylation presynaptic active zone cytoplasmic component glutamatergic synapse GABA-ergic synapse |
| Pathways : KEGG | Wnt signaling pathway Notch signaling pathway Pathways in cancer Chronic myeloid leukemia |
| NDEx Network | CTBP1 |
| Atlas of Cancer Signalling Network | CTBP1 |
| Wikipedia pathways | CTBP1 |
| Orthology - Evolution |
|---|
| OrthoDB | 1487 |
| GeneTree (enSembl) | ENSG00000159692 |
| Phylogenetic Trees/Animal Genes : TreeFam | CTBP1 |
| HOGENOM | Q13363 |
| Homologs : HomoloGene | CTBP1 |
| Homology/Alignments : Family Browser (UCSC) | CTBP1 |
| Gene fusions - Rearrangements |
|---|
| Fusion : Mitelman | MAEA/CTBP1 [4p16.3/4p16.3] |
| Fusion Portal | MAEA 4p16.3 CTBP1 4p16.3 LAML |
| Fusion : Quiver | CTBP1 |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | CTBP1 [hg38] |
| dbVar | CTBP1 |
| ClinVar | CTBP1 |
| Monarch | CTBP1 |
| 1000_Genomes | CTBP1 |
| Exome Variant Server | CTBP1 |
| GNOMAD Browser | ENSG00000159692 |
| Varsome Browser | CTBP1 |
| Genomic Variants (DGV) | CTBP1 [DGVbeta] |
| DECIPHER | CTBP1 [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | CTBP1 |
| Mutations |
|---|
| ICGC Data Portal | CTBP1 |
| TCGA Data Portal | CTBP1 |
| Broad Tumor Portal | CTBP1 |
| OASIS Portal | CTBP1 [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | CTBP1 [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | CTBP1 |
| Mutations and Diseases : HGMD | CTBP1 |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD - Leiden Open Variation Database |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search CTBP1 |
| DgiDB (Drug Gene Interaction Database) | CTBP1 |
| DoCM (Curated mutations) | CTBP1 (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | CTBP1 (select a term) |
| intoGen | CTBP1 |
| Cancer3D | CTBP1(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 194190 602618 617915 |
| Orphanet | |
| DisGeNET | CTBP1 |
| Medgen | CTBP1 |
| Genetic Testing Registry | CTBP1
|
| NextProt | Q13363 [Medical] |
| GENETests | CTBP1 |
| Target Validation | CTBP1 |
| Huge Navigator |
CTBP1 [HugePedia] |
| ClinGen | CTBP1 |
| Clinical trials, drugs, therapy |
|---|
| MyCancerGenome | CTBP1 |
| Protein Interactions : CTD | |
| Pharm GKB Gene | PA26995 |
| Pharos | Q13363 |
| Clinical trial | CTBP1 |
| Miscellaneous |
|---|
| canSAR (ICR) | CTBP1 (select the gene name) |
| Harmonizome | CTBP1 |
| DataMed Index | CTBP1 |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 231 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| EVEX | CTBP1 |
