CTCFL (CCCTC-binding factor like)

2007-02-01  

Identity

HGNC
LOCATION
20q13.31
LOCUSID
ALIAS
BORIS,CT27,CTCF-T,HMGB1L1,dJ579F20.2

Other Information

Locus ID:

NCBI: 140690
MIM: 607022
HGNC: 16234
Ensembl: ENSG00000124092

Variants:

dbSNP: 140690
ClinVar: 140690
TCGA: ENSG00000124092
COSMIC: CTCFL

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124092ENST00000243914Q8NI51
ENSG00000124092ENST00000371196Q8NI51
ENSG00000124092ENST00000422109Q8NI51
ENSG00000124092ENST00000422869Q8NI51
ENSG00000124092ENST00000423479Q8NI51
ENSG00000124092ENST00000426658F5H2V8
ENSG00000124092ENST00000429804Q8NI51
ENSG00000124092ENST00000432255Q8NI51
ENSG00000124092ENST00000433949Q8NI51
ENSG00000124092ENST00000481655V9GYX4
ENSG00000124092ENST00000502686Q8NI51
ENSG00000124092ENST00000539382Q8NI51
ENSG00000124092ENST00000608158V9GYX4
ENSG00000124092ENST00000608263Q8NI51
ENSG00000124092ENST00000608425V9GY73
ENSG00000124092ENST00000608440Q8NI51
ENSG00000124092ENST00000608720V9GZ46
ENSG00000124092ENST00000608903Q8NI51
ENSG00000124092ENST00000609232Q8NI51

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
161409442005Reciprocal binding of CTCF and BORIS to the NY-ESO-1 promoter coincides with derepression of this cancer-testis gene in lung cancer cells.70
180956392007DNA methylation-dependent regulation of BORIS/CTCFL expression in ovarian cancer.56
212968712011Coordinated cancer germline antigen promoter and global DNA hypomethylation in ovarian cancer: association with the BORIS/CTCF expression ratio and advanced stage.44
187656392008BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression.42
179622992007Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors.39
181957092008BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours.39
249833652014Circulating cell-free cancer-testis MAGE-A RNA, BORIS RNA, let-7b and miR-202 in the blood of patients with breast cancer and benign breast diseases.30
168543822006Epigenetic control of CTCFL/BORIS and OCT4 expression in urogenital malignancies.27
210797862010The structural complexity of the human BORIS gene in gametogenesis and cancer.27
173635242007Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression.26

Citation

Dessen P

CTCFL (CCCTC-binding factor like)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/43711/ctcfl