CTDSP1 (CTD small phosphatase 1)

2017-08-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
NIF3,NLI-IF,NLIIF,SCP1
FUSION GENES

Other Information

Locus ID:

NCBI: 58190
MIM: 605323
HGNC: 21614
Ensembl: ENSG00000144579

Variants:

dbSNP: 58190
ClinVar: 58190
TCGA: ENSG00000144579
COSMIC: CTDSP1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144579ENST00000273062Q9GZU7
ENSG00000144579ENST00000273062A0A024R461
ENSG00000144579ENST00000428361H7C1Z7
ENSG00000144579ENST00000431127H7C3E0
ENSG00000144579ENST00000443891Q9GZU7
ENSG00000144579ENST00000452977H7C270

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
156813892005Small CTD phosphatases function in silencing neuronal gene expression.92
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
127212862003A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5.74
170854342006Dephosphorylation of the linker regions of Smad1 and Smad2/3 by small C-terminal domain phosphatases has distinct outcomes for bone morphogenetic protein and transforming growth factor-beta pathways.66
202220122010Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1.21
251970632014C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.15
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
269753712016The Small C-terminal Domain Phosphatase 1 Inhibits Cancer Cell Migration and Invasion by Dephosphorylating Ser(P)68-Twist1 to Accelerate Twist1 Protein Degradation.8
258933002016SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62.7
247694772014A study of substrate specificity for a CTD phosphatase, SCP1, by proteomic screening of binding partners.4

Citation

Dessen P

CTDSP1 (CTD small phosphatase 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/57009/ctdsp1