CUTA (cutA divalent cation tolerance homolog)

2012-11-01  

Identity

HGNC
CUTA
LOCATION
6p21.32
LOCUSID
51596
ALIAS
ACHAP,C6orf82
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51596
MIM: 616953
HGNC: 21101
Ensembl: ENSG00000112514

Variants:

dbSNP: 51596
ClinVar: 51596
TCGA: ENSG00000112514
COSMIC: CUTA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112514ENST00000374484H0YDR4
ENSG00000112514ENST00000374496O60888
ENSG00000112514ENST00000374500O60888
ENSG00000112514ENST00000440279O60888
ENSG00000112514ENST00000482684F2Z2Q5
ENSG00000112514ENST00000488034O60888
ENSG00000112514ENST00000488478C9IZQ5
ENSG00000112514ENST00000494751C9IZG4
ENSG00000112514ENST00000607266O60888
ENSG00000112514ENST00000611509O60888

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
198514452009High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions.51
108009602000Hydrophobic protein that copurifies with human brain acetylcholinesterase: amino acid sequence, genomic organization, and chromosomal localization.8
223517822012CutA divalent cation tolerance homolog (Escherichia coli) (CUTA) regulates β-cleavage of β-amyloid precursor protein (APP) through interacting with β-site APP cleaving protein 1 (BACE1).7
179242042009Characterization of the human CUTA isoform2 present in the stably transfected HeLa cells.5
255579592015Role of copper and the copper-related protein CUTA in mediating APP processing and Aβ generation.4
253448442015Thermodynamic analysis of unusually thermostable CutA1 protein from human brain and its protease susceptibility.3

Citation

Dessen P

CUTA (cutA divalent cation tolerance homolog)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52985/cuta