Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51700
MIM: 608342
HGNC: 24376
Ensembl: ENSG00000166394
Variants:
dbSNP: 51700
ClinVar: 51700
TCGA: ENSG00000166394
COSMIC: CYB5R2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10176 | rasburicase | Chemical | LabelAnnotation | associated | |||
| PA450125 | isosorbide dinitrate | Chemical | LabelAnnotation | associated | |||
| PA450126 | isosorbide mononitrate | Chemical | LabelAnnotation | associated | |||
| PA450475 | metoclopramide | Chemical | LabelAnnotation | associated | |||
| PA451103 | primaquine | Chemical | LabelAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35820466 | 2022 | NADH-Cytochrome B5 reductase 2 suppresses retinal vascular dysfunction through regulation of vascular endothelial growth factor A in diabetic retinopathy. | 0 |
| 35820466 | 2022 | NADH-Cytochrome B5 reductase 2 suppresses retinal vascular dysfunction through regulation of vascular endothelial growth factor A in diabetic retinopathy. | 0 |
| 34978518 | 2021 | Long non-coding RNA MEG3 inhibits neovascularization in diabetic retinopathy by regulating microRNA miR-6720-5p and cytochrome B5 reductase 2. | 11 |
| 34978518 | 2021 | Long non-coding RNA MEG3 inhibits neovascularization in diabetic retinopathy by regulating microRNA miR-6720-5p and cytochrome B5 reductase 2. | 11 |
| 29532410 | 2020 | Intratumoral Heterogeneity for Inactivating Frameshift Mutation of CYB5R2 Gene in Colorectal Cancers. | 3 |
| 29532410 | 2020 | Intratumoral Heterogeneity for Inactivating Frameshift Mutation of CYB5R2 Gene in Colorectal Cancers. | 3 |
| 26323991 | 2015 | Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma. | 35 |
| 26323991 | 2015 | Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma. | 35 |
| 24338690 | 2014 | Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma. | 15 |
| 24338690 | 2014 | Cytochrome b5 reductase 2 is a novel candidate tumor suppressor gene frequently inactivated by promoter hypermethylation in human nasopharyngeal carcinoma. | 15 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 15858218 | 2005 | Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa. | 7 |
| 15858218 | 2005 | Identification of cytochrome-b5 reductase as the enzyme responsible for NADH-dependent lucigenin chemiluminescence in human spermatozoa. | 7 |
Citation
Dessen P
CYB5R2 (cytochrome b5 reductase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40230/cyb5r2
