CYP2F1 (cytochrome P450 family 2 subfamily F member 1)

2007-07-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
C2F1,CYP2F,CYPIIF1

Other Information

Locus ID:

NCBI: 1572
MIM: 124070
HGNC: 2632
Ensembl: ENSG00000197446

Variants:

dbSNP: 1572
ClinVar: 1572
TCGA: ENSG00000197446
COSMIC: CYP2F1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197446ENST00000331105P24903
ENSG00000197446ENST00000439903H0YGI9
ENSG00000197446ENST00000532164P24903
ENSG00000197446ENST00000534009A0A075B795

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Metabolism of xenobiotics by cytochrome P450KEGGko00980
Metabolism of xenobiotics by cytochrome P450KEGGhsa00980
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945
Cytochrome P450 - arranged by substrate typeREACTOMER-HSA-211897
XenobioticsREACTOMER-HSA-211981
CYP2E1 reactionsREACTOMER-HSA-211999
Fatty acidsREACTOMER-HSA-211935

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA10804imatinibChemicalClinicalAnnotationassociatedPD30237583
PA151958383Gastrointestinal Stromal TumorsDiseaseClinicalAnnotationassociatedPD30237583

References

Pubmed IDYearTitleCitations
223978532012Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model.12
125985242003Characterization of the human lung CYP2F1 gene and identification of a novel lung-specific binding motif.8
173271312007Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant.5
173271312007Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant.5
168835222006[Study on genetic polymorphisms of CYP2F1 gene in Guangdong population of China].3
168835222006[Study on genetic polymorphisms of CYP2F1 gene in Guangdong population of China].3
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.3
179436602007CYP2F1 genetic polymorphism: identification of interethnic variations.2
201988572010[The CYP1B1 and CYP2F1 genes polymorphisms frequency in three ethnic groups of Bashkortostan and chronic obstructive pulmonary disease patients].1
201988572010[The CYP1B1 and CYP2F1 genes polymorphisms frequency in three ethnic groups of Bashkortostan and chronic obstructive pulmonary disease patients].1

Citation

Dessen P

CYP2F1 (cytochrome P450 family 2 subfamily F member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47587/cyp2f1