Identity
HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
CP37,CYPIIIA7,P-450(HFL33),P-450111A7,P450-HFLA,P450HLp2
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 1551
MIM: 605340
HGNC: 2640
Ensembl: ENSG00000160870
Variants:
dbSNP: 1551
ClinVar: 1551
TCGA: ENSG00000160870
COSMIC: CYP3A7
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000160870 | ENST00000336374 | P24462 |
| ENSG00000160870 | ENST00000620220 | A0A087WV96 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA164771231 | etonogestrel | Chemical | VariantAnnotation | associated | PK | PD | 30870275 |
| PA165817016 | Kidney Transplantation | Disease | ClinicalAnnotation, VariantAnnotation | associated | PK | 27966227, 28952408 | |
| PA443286 | Adrenal Hyperplasia, Congenital | Disease | VariantAnnotation | associated | PD | ||
| PA443319 | Alzheimer Disease | Disease | VariantAnnotation | not associated | PK | ||
| PA447215 | Psychotic Disorders | Disease | VariantAnnotation | not associated | PK | 23609392 | |
| PA449130 | cortisone acetate | Chemical | VariantAnnotation | associated | PD | ||
| PA449167 | cyclosporine | Chemical | VariantAnnotation | associated | PK | 28952408 | |
| PA449394 | donepezil | Chemical | VariantAnnotation | not associated | PK | ||
| PA451257 | risperidone | Chemical | VariantAnnotation | not associated | PK | 23609392 | |
| PA451578 | tacrolimus | Chemical | ClinicalAnnotation, VariantAnnotation | associated | PK | 27966227 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34688813 | 2022 | CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation. | 4 |
| 34689350 | 2022 | Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations. | 1 |
| 34688813 | 2022 | CYP3A7, CYP3A4, and CYP3A5 genetic polymorphisms in recipients rather than donors influence tacrolimus concentrations in the early stages after liver transplantation. | 4 |
| 34689350 | 2022 | Allele and genotype frequencies of CYP3A4, CYP3A5, CYP3A7, and GSTP1 gene polymorphisms among mainland Tibetan, Mongolian, Uyghur, and Han Chinese populations. | 1 |
| 33438174 | 2021 | Human Fetal Liver Metabolism of Oxycodone Is Mediated by CYP3A7. | 4 |
| 33495599 | 2021 | CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. | 4 |
| 33723203 | 2021 | Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students. | 3 |
| 33866277 | 2021 | Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template. | 4 |
| 33438174 | 2021 | Human Fetal Liver Metabolism of Oxycodone Is Mediated by CYP3A7. | 4 |
| 33495599 | 2021 | CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers. | 4 |
| 33723203 | 2021 | Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students. | 3 |
| 33866277 | 2021 | Development of template systems for ligand interactions of CYP3A5 and CYP3A7 and their distinctions from CYP3A4 template. | 4 |
| 32001245 | 2020 | Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies. | 5 |
| 32146629 | 2020 | CYP3A Polymorphism and Chronic Mercury Intoxication. | 1 |
| 32499339 | 2020 | Urinary Bile Acid Profile of Newborns Born by Cesarean Section Is Characterized by Oxidative Metabolism of Primary Bile Acids: Limited Roles of Fetal-Specific CYP3A7 in Cholate Oxidations. | 2 |
Citation
Dessen P
CYP3A7 (cytochrome P450 family 3 subfamily A member 7)
Atlas Genet Cytogenet Oncol Haematol. 2011-04-01
Online version: http://atlasgeneticsoncology.org/gene/52170/cyp3a7
