CYP4A22 (cytochrome P450 family 4 subfamily A member 22)

2014-11-01  

Identity

HGNC
LOCATION
1p33
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 284541
MIM: 615341
HGNC: 20575
Ensembl: ENSG00000162365

Variants:

dbSNP: 284541
ClinVar: 284541
TCGA: ENSG00000162365
COSMIC: CYP4A22

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162365ENST00000294337A0A0C4DFN9
ENSG00000162365ENST00000371890Q5TCH5
ENSG00000162365ENST00000371891Q5TCH4
ENSG00000162365ENST00000619754A0A087WZX9
ENSG00000162365ENST00000620131A0A087WUY4

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Fatty acid degradationKEGGko00071
Fatty acid degradationKEGGhsa00071
Vascular smooth muscle contractionKEGGhsa04270
Vascular smooth muscle contractionKEGGko04270
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Arachidonic acid metabolismREACTOMER-HSA-2142753
Synthesis of Leukotrienes (LT) and Eoxins (EX)REACTOMER-HSA-2142691
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945
Cytochrome P450 - arranged by substrate typeREACTOMER-HSA-211897
Fatty acidsREACTOMER-HSA-211935
EicosanoidsREACTOMER-HSA-211979
Miscellaneous substratesREACTOMER-HSA-211958

References

Pubmed IDYearTitleCitations
218204962011Genetic polymorphism of CYP4A11 and CYP4A22 genes and in silico insights from comparative 3D modelling in a French population.4
200796722010Molecular modeling study on orphan human protein CYP4A22 for identification of potential ligand binding site.0
311994972019Functional characterization and mechanistic modeling of the human cytochrome P450 enzyme CYP4A22.0

Citation

Dessen P

CYP4A22 (cytochrome P450 family 4 subfamily A member 22)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62258/cyp4a22