Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10800
MIM: 300201
HGNC: 17451
Ensembl: ENSG00000173198
Variants:
dbSNP: 10800
ClinVar: 10800
TCGA: ENSG00000173198
COSMIC: CYSLTR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000173198 | ENST00000373304 | Q9Y271 |
| ENSG00000173198 | ENST00000614798 | Q9Y271 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA134698661 | pranlukast | Chemical | Pathway | associated | |||
| PA450546 | montelukast | Chemical | Pathway | associated | |||
| PA451949 | zafirlukast | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36834820 | 2023 | DNA Methylation and Gene Expression of the Cysteinyl Leukotriene Receptors as a Prognostic and Metastatic Factor for Colorectal Cancer Patients. | 1 |
| 36834820 | 2023 | DNA Methylation and Gene Expression of the Cysteinyl Leukotriene Receptors as a Prognostic and Metastatic Factor for Colorectal Cancer Patients. | 1 |
| 32657253 | 2021 | Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution. | 7 |
| 33837837 | 2021 | The relevance of CYSLTR1 gene polymorphism to the severity of allergic rhinitis and clinical responsiveness of montelukast in children. | 4 |
| 32657253 | 2021 | Methylation of cysteinyl leukotriene receptor 1 genes associates with lung function in asthmatics exposed to traffic-related air pollution. | 7 |
| 33837837 | 2021 | The relevance of CYSLTR1 gene polymorphism to the severity of allergic rhinitis and clinical responsiveness of montelukast in children. | 4 |
| 31732973 | 2020 | CysLT1R expression on ILC2s and effects of CysLT1R antagonist on ILC2 activity in patients with allergic rhinitis. | 7 |
| 32330496 | 2020 | Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1. | 2 |
| 32474153 | 2020 | Cysteinyl leukotriene receptor 1 promotes 5-fluorouracil resistance and resistance-derived stemness in colon cancer cells. | 20 |
| 33077798 | 2020 | Cysteinyl leukotriene receptor 1 modulates autophagic activity in retinal pigment epithelial cells. | 6 |
| 31732973 | 2020 | CysLT1R expression on ILC2s and effects of CysLT1R antagonist on ILC2 activity in patients with allergic rhinitis. | 7 |
| 32330496 | 2020 | Identification of cysteinyl-leukotriene-receptor 1 antagonists as ligands for the bile acid receptor GPBAR1. | 2 |
| 32474153 | 2020 | Cysteinyl leukotriene receptor 1 promotes 5-fluorouracil resistance and resistance-derived stemness in colon cancer cells. | 20 |
| 33077798 | 2020 | Cysteinyl leukotriene receptor 1 modulates autophagic activity in retinal pigment epithelial cells. | 6 |
| 29331588 | 2018 | Antagonism of cysteinyl leukotriene receptor 1 (cysLTR1) by montelukast suppresses cell senescence of chondrocytes. | 11 |
Citation
Dessen P
CYSLTR1 (cysteinyl leukotriene receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46481/cysltr1
