CYTH3 (cytohesin 3)

2006-10-01  

Identity

HGNC
LOCATION
7p22.1
LOCUSID
ALIAS
ARNO3,GRP1,PSCD3,cytohesin-3
FUSION GENES

Other Information

Locus ID:

NCBI: 9265
MIM: 605081
HGNC: 9504
Ensembl: ENSG00000008256

Variants:

dbSNP: 9265
ClinVar: 9265
TCGA: ENSG00000008256
COSMIC: CYTH3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000008256ENST00000350796O43739
ENSG00000008256ENST00000396741O43739

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072
Intra-Golgi and retrograde Golgi-to-ER trafficREACTOMER-HSA-6811442
Intra-Golgi trafficREACTOMER-HSA-6811438

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
249669202014Cytohesin-3 is upregulated in hepatocellular carcinoma and contributes to tumor growth and vascular invasion.12
249669202014Cytohesin-3 is upregulated in hepatocellular carcinoma and contributes to tumor growth and vascular invasion.12
224545182012Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling.13
224545182012Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling.13
219327732011The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).18
219327732011The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3).18
158789552005General receptor for phosphoinositides 1, a novel repressor of thyroid hormone receptor action that prevents deoxyribonucleic acid binding.1
158789552005General receptor for phosphoinositides 1, a novel repressor of thyroid hormone receptor action that prevents deoxyribonucleic acid binding.1

Citation

Dessen P

CYTH3 (cytohesin 3)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43434/cyth3