DAND5 (DAN domain BMP antagonist family member 5)

2008-10-01  

Identity

HGNC
LOCATION
19p13.13
LOCUSID
ALIAS
CER2,CERL2,CKTSF1B3,COCO,CRL2,DANTE,GREM3,SP1
FUSION GENES

Other Information

Locus ID:

NCBI: 199699
MIM: 609068
HGNC: 26780
Ensembl: ENSG00000179284

Variants:

dbSNP: 199699
ClinVar: 199699
TCGA: ENSG00000179284
COSMIC: DAND5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179284ENST00000317060Q8N907
ENSG00000179284ENST00000585548K7EQF6

Expression (GTEx)

0
1
2
3
4
5
6
7

Pathways

PathwaySourceExternal ID
Developmental BiologyREACTOMER-HSA-1266738
Signaling by NODALREACTOMER-HSA-1181150
Regulation of signaling by NODALREACTOMER-HSA-1433617

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
229018082012The BMP inhibitor Coco reactivates breast cancer cells at lung metastatic sites.133
269084522016The BMP inhibitor DAND5 in serum predicts poor survival in breast cancer.4
287387922017Functional study of DAND5 variant in patients with Congenital Heart Disease and laterality defects.2
306850692019Reduced levels of Coco in sera of multiple sclerosis patients: A potential role in neuro-regeneration failure.1

Citation

Dessen P

DAND5 (DAN domain BMP antagonist family member 5)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50397/dand5