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DBF4 (DBF4 zinc finger)

Identity

Alias_namesDBF4 homolog (S. cerevisiae)
Alias_symbol (synonym)ASK
chif
ZDBF1
DBF4A
Other aliasCHIF
HGNC (Hugo) DBF4
LocusID (NCBI) 10926
Atlas_Id 50062
Location 7q21.12  [Link to chromosome band 7q21]
Location_base_pair Starts at 87876229 and ends at 87909541 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DBF4   17364
Cards
Entrez_Gene (NCBI)DBF4  10926  DBF4 zinc finger
AliasesASK; CHIF; DBF4A; ZDBF1
GeneCards (Weizmann)DBF4
Ensembl hg19 (Hinxton)ENSG00000006634 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000006634 [Gene_View]  ENSG00000006634 [Sequence]  chr7:87876229-87909541 [Contig_View]  DBF4 [Vega]
ICGC DataPortalENSG00000006634
TCGA cBioPortalDBF4
AceView (NCBI)DBF4
Genatlas (Paris)DBF4
WikiGenes10926
SOURCE (Princeton)DBF4
Genetics Home Reference (NIH)DBF4
Genomic and cartography
GoldenPath hg38 (UCSC)DBF4  -     chr7:87876229-87909541 +  7q21.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DBF4  -     7q21.12   [Description]    (hg19-Feb_2009)
GoldenPathDBF4 - 7q21.12 [CytoView hg19]  DBF4 - 7q21.12 [CytoView hg38]
ImmunoBaseENSG00000006634
Mapping of homologs : NCBIDBF4 [Mapview hg19]  DBF4 [Mapview hg38]
OMIM604281   
Gene and transcription
Genbank (Entrez)AB028069 AB028070 AF160249 AF160876 AK022969
RefSeq transcript (Entrez)NM_001318060 NM_001318061 NM_001318062 NM_006716
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DBF4
Cluster EST : UnigeneHs.485380 [ NCBI ]
CGAP (NCI)Hs.485380
Alternative Splicing GalleryENSG00000006634
Gene ExpressionDBF4 [ NCBI-GEO ]   DBF4 [ EBI - ARRAY_EXPRESS ]   DBF4 [ SEEK ]   DBF4 [ MEM ]
Gene Expression Viewer (FireBrowse)DBF4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10926
GTEX Portal (Tissue expression)DBF4
Human Protein AtlasENSG00000006634-DBF4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBU7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBU7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBU7
Splice isoforms : SwissVarQ9UBU7
PhosPhoSitePlusQ9UBU7
Domaine pattern : Prosite (Expaxy)ZF_DBF4 (PS51265)   
Domains : Interpro (EBI)BRCT_dom    Znf_DBF    Znf_DBF_sf   
Domain families : Pfam (Sanger)zf-DBF (PF07535)   
Domain families : Pfam (NCBI)pfam07535   
Domain families : Smart (EMBL)ZnF_DBF (SM00586)  
Conserved Domain (NCBI)DBF4
DMDM Disease mutations10926
Blocks (Seattle)DBF4
PDB (RSDB)4F99    4F9A    4F9B    4F9C   
PDB Europe4F99    4F9A    4F9B    4F9C   
PDB (PDBSum)4F99    4F9A    4F9B    4F9C   
PDB (IMB)4F99    4F9A    4F9B    4F9C   
Structural Biology KnowledgeBase4F99    4F9A    4F9B    4F9C   
SCOP (Structural Classification of Proteins)4F99    4F9A    4F9B    4F9C   
CATH (Classification of proteins structures)4F99    4F9A    4F9B    4F9C   
SuperfamilyQ9UBU7
Human Protein Atlas [tissue]ENSG00000006634-DBF4 [tissue]
Peptide AtlasQ9UBU7
HPRD10371
IPIIPI00170805   IPI00744939   IPI00925436   IPI00925654   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBU7
IntAct (EBI)Q9UBU7
FunCoupENSG00000006634
BioGRIDDBF4
STRING (EMBL)DBF4
ZODIACDBF4
Ontologies - Pathways
QuickGOQ9UBU7
Ontology : AmiGOG1/S transition of mitotic cell cycle  nucleic acid binding  protein binding  nucleus  nucleus  nucleoplasm  DNA replication  enzyme activator activity  zinc ion binding  positive regulation of nuclear cell cycle DNA replication  nuclear body  Dbf4-dependent protein kinase complex  protein serine/threonine kinase activator activity  positive regulation of protein serine/threonine kinase activity  regulation of cell cycle phase transition  
Ontology : EGO-EBIG1/S transition of mitotic cell cycle  nucleic acid binding  protein binding  nucleus  nucleus  nucleoplasm  DNA replication  enzyme activator activity  zinc ion binding  positive regulation of nuclear cell cycle DNA replication  nuclear body  Dbf4-dependent protein kinase complex  protein serine/threonine kinase activator activity  positive regulation of protein serine/threonine kinase activity  regulation of cell cycle phase transition  
Pathways : KEGGCell cycle   
NDEx NetworkDBF4
Atlas of Cancer Signalling NetworkDBF4
Wikipedia pathwaysDBF4
Orthology - Evolution
OrthoDB10926
GeneTree (enSembl)ENSG00000006634
Phylogenetic Trees/Animal Genes : TreeFamDBF4
HOGENOMQ9UBU7
Homologs : HomoloGeneDBF4
Homology/Alignments : Family Browser (UCSC)DBF4
Gene fusions - Rearrangements
Fusion : QuiverDBF4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDBF4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DBF4
dbVarDBF4
ClinVarDBF4
1000_GenomesDBF4 
Exome Variant ServerDBF4
ExAC (Exome Aggregation Consortium)ENSG00000006634
GNOMAD BrowserENSG00000006634
Varsome BrowserDBF4
Genetic variants : HAPMAP10926
Genomic Variants (DGV)DBF4 [DGVbeta]
DECIPHERDBF4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDBF4 
Mutations
ICGC Data PortalDBF4 
TCGA Data PortalDBF4 
Broad Tumor PortalDBF4
OASIS PortalDBF4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDBF4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDBF4
Mutations and Diseases : HGMDDBF4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DBF4
DgiDB (Drug Gene Interaction Database)DBF4
DoCM (Curated mutations)DBF4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DBF4 (select a term)
intoGenDBF4
Cancer3DDBF4(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604281   
Orphanet
DisGeNETDBF4
MedgenDBF4
Genetic Testing Registry DBF4
NextProtQ9UBU7 [Medical]
TSGene10926
GENETestsDBF4
Target ValidationDBF4
Huge Navigator DBF4 [HugePedia]
snp3D : Map Gene to Disease10926
BioCentury BCIQDBF4
ClinGenDBF4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10926
Chemical/Pharm GKB GenePA142672016
Clinical trialDBF4
Miscellaneous
canSAR (ICR)DBF4 (select the gene name)
DataMed IndexDBF4
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDBF4
EVEXDBF4
GoPubMedDBF4
iHOPDBF4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:39:46 CET 2019
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