DBF4B (DBF4 zinc finger B)

2016-10-01  

Identity

HGNC
LOCATION
17q21.31
LOCUSID
ALIAS
ASKL1,CHIFB,DRF1,ZDBF1B
FUSION GENES

Other Information

Locus ID:

NCBI: 80174
MIM: 611661
HGNC: 17883
Ensembl: ENSG00000161692

Variants:

dbSNP: 80174
ClinVar: 80174
TCGA: ENSG00000161692
COSMIC: DBF4B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000161692ENST00000315005Q8NFT6
ENSG00000161692ENST00000393547Q8NFT6
ENSG00000161692ENST00000526924B4E099

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
191116652008The role of Dbf4/Drf1-dependent kinase Cdc7 in DNA-damage checkpoint control.29
120654292002Drf1, a novel regulatory subunit for human Cdc7 kinase.28
156682322005A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases.26
292623222017SRSF1 Prevents DNA Damage and Promotes Tumorigenesis through Regulation of DBF4B Pre-mRNA Splicing.6

Citation

Dessen P

DBF4B (DBF4 zinc finger B)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56410/dbf4b