DCC (deleted in colorectal carcinoma)

Identity

Other names	CRC18
	CRCR1
HGNC	DCC
Location	18q21.1
Location_base_pair	Starts at 48120569 and ends at 49311780 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DCC   2701
Entrez_Gene	DCC  1630  deleted in colorectal carcinoma
	Cards
GeneCards	DCC
Ensembl	DCC [Search_View]   ENSG00000187323 [Gene_View]
Genatlas	DCC
GeneLynx	DCC
eGenome	DCC
euGene	1630
	Genomic and cartography
GoldenPath	DCC  -  18q21.1   chr18:48120569-49311780 +  18q21.2   [Description]    (hg18-March_2006)
Ensembl	DCC - 18q21.2 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DCC
	Gene and transcription
Genbank	AK310385 [ ENTREZ ]
Genbank	AW949550 [ ENTREZ ]
Genbank	BC036524 [ ENTREZ ]
Genbank	BC152808 [ ENTREZ ]
Genbank	M32292 [ ENTREZ ]
RefSeq	NM_005215 [ SRS ]    NM_005215 [ ENTREZ ]
RefSeq	AC_000061 [ SRS ]    AC_000061 [ ENTREZ ]
RefSeq	AC_000150 [ SRS ]    AC_000150 [ ENTREZ ]
RefSeq	NC_000018 [ SRS ]    NC_000018 [ ENTREZ ]
RefSeq	NT_010966 [ SRS ]    NT_010966 [ ENTREZ ]
RefSeq	NW_001838468 [ SRS ]    NW_001838468 [ ENTREZ ]
RefSeq	NW_927106 [ SRS ]    NW_927106 [ ENTREZ ]
AceView	DCC AceView - NCBI
Unigene	Hs.579550 [ SRS ]    Hs.579550 [ NCBI ]     HS579550 [ spliceNest ]
Fast-db	4571 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P43146 [ SRS]    P43146 [ EXPASY ]     P43146 [ INTERPRO ]     P43146 [ UNIPROT ]
Prosite	PS50853 FN3 [ SRS ]    PS50853 FN3 [ Expasy ]
Prosite	PS50835 IG_LIKE [ SRS ]    PS50835 IG_LIKE [ Expasy ]
Interpro	IPR008957 Fibronectin_typ-III-like_fold [ SRS ]    IPR008957 Fibronectin_typ-III-like_fold [ EBI ]
Interpro	IPR003961 FN_III [ SRS ]    IPR003961 FN_III [ EBI ]
Interpro	IPR003962 FnIII_subd [ SRS ]    IPR003962 FnIII_subd [ EBI ]
Interpro	IPR007110 Ig-like [ SRS ]    IPR007110 Ig-like [ EBI ]
Interpro	IPR013783 Ig-like_fold [ SRS ]    IPR013783 Ig-like_fold [ EBI ]
Interpro	IPR013098 Ig_I-set [ SRS ]    IPR013098 Ig_I-set [ EBI ]
Interpro	IPR003599 Ig_sub [ SRS ]    IPR003599 Ig_sub [ EBI ]
Interpro	IPR003598 Ig_sub2 [ SRS ]    IPR003598 Ig_sub2 [ EBI ]
Interpro	IPR010560 Neogenin_C [ SRS ]    IPR010560 Neogenin_C [ EBI ]
CluSTr	P43146
Pfam	PF00041 fn3 [ SRS ]    PF00041 fn3 [ Sanger ]    pfam00041 [ NCBI-CDD ]
Pfam	PF07679 I-set [ SRS ]    PF07679 I-set [ Sanger ]    pfam07679 [ NCBI-CDD ]
Pfam	PF06583 Neogenin_C [ SRS ]    PF06583 Neogenin_C [ Sanger ]    pfam06583 [ NCBI-CDD ]
Smart	SM00060 FN3 [EMBL]
Smart	SM00409 IG [EMBL]
Smart	SM00408 IGc2 [EMBL]
Blocks	P43146
PDB	2ED7 [ SRS ]    2ED7 [ PdbSum ],   2ED7 [ IMB ]   2ED7 [ RSDB ]
PDB	2ED8 [ SRS ]    2ED8 [ PdbSum ],   2ED8 [ IMB ]   2ED8 [ RSDB ]
PDB	2ED9 [ SRS ]    2ED9 [ PdbSum ],   2ED9 [ IMB ]   2ED9 [ RSDB ]
PDB	2EDB [ SRS ]    2EDB [ PdbSum ],   2EDB [ IMB ]   2EDB [ RSDB ]
PDB	2EDD [ SRS ]    2EDD [ PdbSum ],   2EDD [ IMB ]   2EDD [ RSDB ]
PDB	2EDE [ SRS ]    2EDE [ PdbSum ],   2EDE [ IMB ]   2EDE [ RSDB ]
HPRD	00391
	Protein Interaction databases
DIP	P43146
IntAct	P43146
	Polymorphism : SNP, mutations, diseases
OMIM	120470    [ map ]
GENECLINICS	120470
SNP	DCC [dbSNP-NCBI]
SNP	NM_005215 [SNP-NCI]
SNP	DCC [GeneSNPs - Utah]  DCC] [HGBASE - SRS]
HAPMAP	DCC [HAPMAP]
HGMD	DCC
	General knowledge
Family Browser	DCC [UCSC Family Browser]
SOURCE	NM_005215
SMD	Hs.579550
SAGE	Hs.579550
GO	transcription coactivator activity [Amigo]  transcription coactivator activity
GO	netrin receptor activity [Amigo]  netrin receptor activity
GO	protein binding [Amigo]  protein binding
GO	apoptosis [Amigo]  apoptosis
GO	induction of apoptosis [Amigo]  induction of apoptosis
GO	multicellular organismal development [Amigo]  multicellular organismal development
GO	axon guidance [Amigo]  axon guidance
GO	membrane [Amigo]  membrane
GO	integral to membrane [Amigo]  integral to membrane
GO	axon [Amigo]  axon
GO	negative regulation of cell cycle [Amigo]  negative regulation of cell cycle
KEGG	Axon guidance
KEGG	Colorectal cancer
PubGene	DCC
TreeFam	DCC
CTD	1630 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DCC Related clones (RZPD - Berlin)
	PubMed
PubMed	53 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:37:37 2008